A7MK11
Gene name |
mtnC |
Protein name |
Enolase-phosphatase E1 |
Names |
2,3-diketo-5-methylthio-1-phosphopentane phosphatase |
Species |
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) |
KEGG Pathway |
esa:ESA_02725 |
EC number |
3.1.3.77: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7MK11
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7MK11-F1 | Predicted | AlphaFoldDB |
No variants for A7MK11
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7MK11 | |||||
No associated diseases with A7MK11
No regional properties for A7MK11
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A7MK11 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.77 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity | Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P. |
| 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity | Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene. |
| acireductone synthase activity | Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| L-methionine salvage from methylthioadenosine | The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. |
| L-methionine salvage from S-adenosylmethionine | The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIRAIVTDIE | GTTTDIRFVH | NVLFPYARER | LERFIRSGEQ | REPVNLLLNE | LRGEIHAPAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SVDQLIETLF | KFMDEDRKSP | ALKSIQGYIW | REGYVNGDFT | GHLYPDVVPA | LRRWSAQDID |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IYIYSSGSVP | AQKLLFSHSD | EGDVTELLSG | FFDTHVGAKR | QVSSYRNISM | KTGVPVHQML |
| 190 | 200 | 210 | 220 | ||
| FLSDIREELD | AAREAGWKTV | QLIRGEPDTQ | STHRQVSSFD | DIHPEQIPT |