A7MJ63
Gene name |
cysJ |
Protein name |
Sulfite reductase [NADPH] flavoprotein alpha-component |
Names |
SiR-FP |
Species |
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) |
KEGG Pathway |
esa:ESA_00533 |
EC number |
1.8.1.2: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7MJ63
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7MJ63-F1 | Predicted | AlphaFoldDB |
No variants for A7MJ63
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7MJ63 | |||||
No associated diseases with A7MJ63
1 regional properties for A7MJ63
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Phosphoadenosine phosphosulphate reductase | 48 - 219 | IPR002500 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.8.1.2 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| sulfite reductase (NADPH) activity | Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cysteine biosynthetic process | The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid. |
| hydrogen sulfide biosynthetic process | The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S. |
| sulfate assimilation | The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTQAPPNAL | LPLSPEQLAR | LQTATHDFTP | TQLAWLSGYF | WGMVNQQPGA | AVMQKPAAPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SVITLISASQ | TGNARRVAEA | LRDDLLAAQL | NVNLVNAGDY | KFKQIAQEKL | LIVVASTQGE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GDPPEEAVAL | HKFLLSKKAP | KLDGTAFAVF | GLGDTSYEHF | CQAGKDFDTR | LAELGAERLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DRVDADVEYQ | AAAQAWRQRV | VDVLKARVPK | EAPSQAAITA | SGAVNLVDST | PYTKESPLTA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLSVNQKITG | RHSEKDVRHI | EIDLGDAGLR | YQPGDALGVW | YQNDPALVQE | LLELLWLKGD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EPVTVGEKTL | PLSEALQWHF | ELTVNTAAIV | ENYATLTRSE | ALLPLVGDKA | KLQDYAARTP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IVDMVRFAPA | QLEADQLLGL | LRPLTPRLYS | IASSQAEVEN | EVHITVGVVR | FDIEGRVRAG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GASSYLADRL | EEDSEVRVFI | EHNDNFRLPA | TPETPVIMIG | PGTGIAPFRA | FMQQREADGA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TGKNWLFFGN | PHFTEDFLYQ | VEWQRYVKEG | LLTRIDLAWS | RDQDHKIYVQ | DKIREQGAEL |
| 550 | 560 | 570 | 580 | 590 | |
| WRWLQEGAHL | YVCGDANRMA | KDVEQALLEV | IAAYGGMDAE | AADEYLSELR | VERRYQRDVY |