A7MGR4
Gene name |
clcA |
Protein name |
H(+)/Cl(-) exchange transporter ClcA |
Names |
|
Species |
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) |
KEGG Pathway |
esa:ESA_03185 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7MGR4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7MGR4-F1 | Predicted | AlphaFoldDB |
No variants for A7MGR4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7MGR4 | |||||
No associated diseases with A7MGR4
9 regional properties for A7MGR4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | AAA+ ATPase domain | 202 - 348 | IPR003593-1 |
| domain | AAA+ ATPase domain | 603 - 774 | IPR003593-2 |
| domain | ATPase, AAA-type, core | 207 - 307 | IPR003959-1 |
| domain | ATPase, AAA-type, core | 602 - 767 | IPR003959-2 |
| domain | Clp, repeat (R) domain | 3 - 150 | IPR004176 |
| conserved_site | ClpA/B, conserved site 1 | 298 - 310 | IPR018368 |
| domain | Clp ATPase, C-terminal | 773 - 862 | IPR019489 |
| conserved_site | ClpA/B, conserved site 2 | 637 - 655 | IPR028299 |
| domain | ClpA/ClpB, AAA lid domain | 346 - 448 | IPR041546 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| voltage-gated chloride channel activity | Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKSQTIPTRR | VRGFRRAAVI | RQLLSRDKTP | LTILLLASLT | GVLAGLAGVA | FEKAVAWVTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HRIEGLAQVA | HIPWLVWLLA | FLFSALLAMV | GYFLVRRFAP | EAGGSGIPEI | EGALEELRPV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RWWRVLPVKF | FGGMGTLGAG | MVLGREGPMV | QMGGNIGRMV | LDIFHRPDAE | ARHTLLATGA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAGLAAAFNA | PLAGILFIIE | EMRTQFHYNL | ISIKAVFTGV | IMSTIVFRIF | NGEKSVIEVG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QLTDAPVYTL | WLYLLLGIIF | GAVGPLFNRL | VLGMQDVFAR | IHGGNTTRWV | LLGGAIGGAC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GLLALWEPAA | AGGGFGLIPI | AAAGNFTVGM | LLFIFIARVV | TTVFCFSSGA | PGGIFAPMLA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGTLLGSAFG | MACAAWFPQW | HLQAGTFAIA | GMGALLAASV | RAPITGIVLV | LEMTDNYQLI |
| 430 | 440 | 450 | 460 | ||
| LPMIITCLGA | TLLAQFLGGK | PLYSTILART | LAKQEAERQA | QADGRNT |