A7ME76

PR
Gene name
malT
Protein name
HTH-type transcriptional regulator MalT
Names
ATP-dependent transcriptional activator MalT
Species
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
KEGG Pathway
esa:ESA_04320
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

793-862 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7ME76

Entry ID Method Resolution Chain Position Source
AF-A7ME76-F1 Predicted AlphaFoldDB

No variants for A7ME76

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7ME76

No associated diseases with A7ME76

3 regional properties for A7ME76

Type Name Position InterPro Accession
conserved_site Translation initiation factor 3, conserved site 72 - 85 IPR019813
domain Translation initiation factor 3, N-terminal 22 - 90 IPR019814
domain Translation initiation factor 3, C-terminal 97 - 183 IPR019815

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLIPSKLSRP VRLEHTVVRE RLLAKLSGAS NYRLALITSP AGYGKTTLIS QWAAGKTELG
70 80 90 100 110 120
WYSLDEGDNQ PERFASYLIA AIQQATGGHC ASSEVMAQKR QYASLSSLFA QLFIELAAWP
130 140 150 160 170 180
RPLFLVIDDY HLITNPVIHE AMRFFLRHQP DHLTLVVLSR NLPQLGIANL RVREQLLEIG
190 200 210 220 230 240
SQQLAFTHQE ARQFFDCRLS QPIEPAQSNR LCDDVAGWAT ALQLIALSAR QNTGAVHQSA
250 260 270 280 290 300
RRLAGINASH LSDYLVDEVL NNVDNDTRQF LLKSALLRSM NDALIARVTG EENGQMRLEE
310 320 330 340 350 360
IERQGLFLQR MDDSGEWFSY HPLFGSFLRQ RCQWELSTEL PDIHRAAAES WMAQGFPSEA
370 380 390 400 410 420
IHHALAAGDA SMLRDILLNH AWGLFNHSEL TLLEQSLKAL PWESLLANPR LVLLQAWLMQ
430 440 450 460 470 480
SQHRYSEVNT LLARAEQEMK GEMDDTLHGE FNALRAQVAI NDGDPDEAER LAMVALETLP
490 500 510 520 530 540
LANFYSRIVA TSVHGEVLHC KGDLTKSLSV MQQTELMARR HDVWHYALWS LIQQSEILFA
550 560 570 580 590 600
QGFLQAAWET QEKAFTLIQE QHLEQLPLHE FLLRIRAQLL WAWARLDEAE ACARTGMTVL
610 620 630 640 650 660
ANYQPQQQLQ CLALLVQCSL ARGDLDNARS HLNRLENLLG NGHYHSDWVS NADKVRVIYW
670 680 690 700 710 720
QMTGDKAAAA AWLRQTPKPA FANNHFLQSQ WRNIARVQIL LGDYEPAEMV LEELNENARS
730 740 750 760 770 780
LRLMSDINRN LLLLNQLYWN AGRKSDAQRV LMEALTLANR TGFISHFVIE GEAMAQQLRQ
790 800 810 820 830 840
LLQLNTLPEI EQHRAQRILR DINQHHRHKF AHFDENFVNK LLNHPEVPEL IRTSPLTQRE
850 860 870 880 890 900
WQVLGLIYSG YSNDQIAGEL DVAATTIKTH IRNLYQKLGV AHRQDAVQHA QQLLKMMGYG
V