A7ME23

PR
Gene name
kefB
Protein name
Glutathione-regulated potassium-efflux system protein KefB
Names
K(+)/H(+) antiporter
Species
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
KEGG Pathway
esa:ESA_04389
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

355-426 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7ME23

Entry ID Method Resolution Chain Position Source
AF-A7ME23-F1 Predicted AlphaFoldDB

No variants for A7ME23

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7ME23

No associated diseases with A7ME23

5 regional properties for A7ME23

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 150 - 483 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 56 - 133 IPR004365
domain Aminoacyl-tRNA synthetase, class II 179 - 480 IPR006195
domain Lysyl-tRNA synthetase, class II, C-terminal 165 - 486 IPR018149
domain Lysine-tRNA ligase, class II, N-terminal 54 - 161 IPR044136

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
glutathione-regulated potassium exporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
solute:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEGSDLLLAG ILFLFAAVVA VPIAARLGIG AVLGYLLAGI AIGPWGLGFI SDVDEILHFS
70 80 90 100 110 120
ELGVVFLMFL IGLELNPSKL WKLRRSIFGI GAAQVLLSAV VLAGLLMLTD FAWQAAVVGG
130 140 150 160 170 180
IGLAMSSTAM ALQLMRDKGM NRTEGGQLGF SVLLFQDLAV IPALAMVPLL AGNGDEHPDW
190 200 210 220 230 240
LKIGMKVLAF AVMLVGGRYL LRPVFRFIAG SGVREVFTAA ALLLVLGSAL FMDLLGLSMA
250 260 270 280 290 300
LGTFIAGILL AESEYRHELE IAIEPFKGLL LGLFFISVGM ALNLGVLYTH ILWVVMSVVV
310 320 330 340 350 360
LVSVKMAVLY GLGRFQGLRR TERLPFAGVL SQGGEFAFVL FSSASSQKLF HNDQMALLLV
370 380 390 400 410 420
TVTLSMMTTP LVMKGIDRLL ARHFNAPDED AEMPYVEDDK PQVIIVGFGR FGQVIGRLLM
430 440 450 460 470 480
ANKMRITVLE RDISAVNLMR KYGYKVYYGD ATELELLRAA GAESAQSIVV TCNDPEDTMR
490 500 510 520 530 540
IVHLCQQHFP QMEILARARG RVEAHELLQA GVKQFSRETF SSALELGRKT LISLGMHPHQ
550 560 570 580 590 600
AQRAQLHFRR LDMRMLRELM PVHTDNAQIS RVREARRELE EIFHREMQQE RRQLDGWDEF
E