A7I8L8

PR
Gene name
aroA
Protein name
3-phosphoshikimate 1-carboxyvinyltransferase
Names
5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS
Species
Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
KEGG Pathway
mbn:Mboo_1562
EC number
2.5.1.19: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7I8L8

Entry ID Method Resolution Chain Position Source
AF-A7I8L8-F1 Predicted AlphaFoldDB

No variants for A7I8L8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7I8L8

No associated diseases with A7I8L8

2 regional properties for A7I8L8

Type Name Position InterPro Accession
domain Enolpyruvate transferase domain 11 - 416 IPR001986
conserved_site 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site 335 - 353 IPR023193

Functions

Description
EC Number 2.5.1.19 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
3-phosphoshikimate 1-carboxyvinyltransferase activity Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.

3 GO annotations of biological process

Name Definition
aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
chorismate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIVTLPARSG IELSVTTPPS KSYTHRALIA AALAQGRSTI VRPLMADDTK LTIASLMKLG
70 80 90 100 110 120
VAIHADQHNI MLEGCDGSFP NTPGTVLDLD NSGTSLRLLA SAALLATYPV TLTGSARMQE
130 140 150 160 170 180
RPLGPLAHTL NDLGGMVIFT KKEGYPPVTI GGRLLGGTAT IDGSQSSQFA SSVMMAAPYS
190 200 210 220 230 240
KGPVDLTVTG TPASQSYLDI TAGVMTDFGA VIRREGYRRF LVSNCNHYTG RTFVVEGDYS
250 260 270 280 290 300
SASYFFALAA ICGGKVTVAG LAPDSVQGDR LFLDALQRMG CEVTYAHDGV TVENQGPLTG
310 320 330 340 350 360
ITINMSSAPD TVQTLCMVAA VARTPTIITG IGHLKFKESD RIAVTADRLR MLGGIVTAER
370 380 390 400 410 420
DRIVIQPATL HGGRIDPVND HRTAMSFAVL GLGIGGITIT GAECVNKSFP GFWEILSKVM
E