A7I145
Gene name |
mnmE |
Protein name |
tRNA modification GTPase MnmE |
Names |
|
Species |
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) |
KEGG Pathway |
cha:CHAB381_0654 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7I145
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7I145-F1 | Predicted | AlphaFoldDB |
No variants for A7I145
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7I145 | |||||
No associated diseases with A7I145
5 regional properties for A7I145
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 238 - 377 | IPR005225 |
| domain | GTP binding domain | 239 - 355 | IPR006073 |
| domain | GTP-binding protein TrmE, N-terminal | 3 - 141 | IPR018948 |
| domain | MnmE, helical domain | 144 - 463 | IPR025867 |
| domain | TrmE-type guanine nucleotide-binding domain | 236 - 391 | IPR031168 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSETIVAVAT | AHGIGGISIV | RLSGENALSL | SDILINKNRK | KNKTQNSVSS | SQNRIQNFKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| INLKPRYATL | CELYDNDGNF | MDESVVIYYK | SPNSFTGEDI | VEFQIHGGFT | LENLIMDELI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TNGARIAMPG | EFSKRAFLND | KMDLSKAEAI | QSIILSRSKS | AAKILARNLH | GELKNFVIDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RKEIVKTMAF | VETCIDYADD | DLPNDILDKI | QNLLSENITK | IDEITQISAS | RRGLLEGFKV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AIIGKPNVGK | SSILNSLLKF | SRAIVSDEAG | TTRDRIEENL | QIGSHLIRII | DTAGIRKSEN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SVENIGISYS | IKAANEADII | LAVFDASREF | DKEDEKIFEI | LQNQKDKKII | KILNKIDLAL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KFKAGNSDNF | LKISAKNDTK | IITKVLNDYL | NSQNFDGIML | SSNRQIMAFS | NAGKALKRAQ |
| 430 | 440 | 450 | 460 | ||
| NLLNENSLEL | FAFELNIAIK | EIASIYKPFE | RDEILESMFS | NFCLGK |