A7HMM7

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)
KEGG Pathway
fno:Fnod_1313
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

795-864 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7HMM7

Entry ID Method Resolution Chain Position Source
AF-A7HMM7-F1 Predicted AlphaFoldDB

No variants for A7HMM7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7HMM7

No associated diseases with A7HMM7

9 regional properties for A7HMM7

Type Name Position InterPro Accession
domain Helicase, C-terminal 433 - 632 IPR001650
conserved_site SEC-C motif 892 - 909 IPR004027
domain SecA DEAD-like, N-terminal 6 - 398 IPR011115
domain SecA Wing/Scaffold 615 - 826 IPR011116
domain SecA, preprotein cross-linking domain 228 - 354 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 616 IPR014018
conserved_site SecA conserved site 496 - 511 IPR020937
domain SecA, C-terminal helicase domain 416 - 586 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGNLKKIFD KNEIEIRKAR KIVERINQLD EKARKTSFEE MKSYILQYKG KLENIEELDE
70 80 90 100 110 120
HLEQVFAYVR ETARRTVGMR HFDVQLIGGI VLHKGKIAEM KTGEGKTLVA TAPIVLNSLM
130 140 150 160 170 180
NRNIHVVTVN DYLAKRDAMW MGPIYLALGL RVGIINTTGK AYEVVWKNPE LAEKGLKENY
190 200 210 220 230 240
CVWPDDYDGE FLSDEMKVKK AVEAFEVDII EVSKKEAYRC DVTYGTNSEF GFDYLRDNLV
250 260 270 280 290 300
VSLDDKVQMG HFYAIVDEVD SILIDEARTP LIISGPSKNN ASVYKHFYQI AKRLEKDKHF
310 320 330 340 350 360
KVDEEHRTVL LTDEGIEYLE KLLGVDNLYD PANVNSIYHI TNSLKAIHLF KKDVDYIVHN
370 380 390 400 410 420
GQVLIVDEFT GRVLPGRRYS GGLHQAIEAK EGVPIKEESI TYATITYQNY FRMYEKLAGM
430 440 450 460 470 480
TGTAKTEEQE FKAIYGMDVV VIPTHKPMIR IDHDDLIYRS VEEKYKAIVE EIKKRHEKGQ
490 500 510 520 530 540
PVLVGTTSIE KSEKLSEMLK KEGIPHQVLN AKYHEKEAQI VAQAGQKGMV TIATNMAGRG
550 560 570 580 590 600
TDIKLGPGVK ELGGLLIIGT ERHESRRIDN QLRGRSGRQG DPGESIFFLS VEDDLMRIFG
610 620 630 640 650 660
GDRIQKVMDM VKIEPGQPIY HPLLTKLIEQ VQKKVEGINF SVRKYLLELD SVLDTQRRAI
670 680 690 700 710 720
YGYRDNILER DVDDFISEAI DNFVEARIEE FCSGVEWDWE GLKNSFAVIK DFVKIDTKID
730 740 750 760 770 780
DKEKLKQDII EQITKAYRLK KEEFGEDFEH VAKFIVLRII DENWRQYLEE VEHVKESIRL
790 800 810 820 830 840
RSYGQKDPVL EFKKETYDMF NDMMMRTYEL SVSYLLNLRR VDNKAEEESK KELAKVSTVH
850 860
DEFRLIAEES KDSDKKKPKL KIKR