A7H9F8

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Anaeromyxobacter sp (strain Fw109-5)
KEGG Pathway
afw:Anae109_1146
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

672-722 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7H9F8

Entry ID Method Resolution Chain Position Source
AF-A7H9F8-F1 Predicted AlphaFoldDB

No variants for A7H9F8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7H9F8

No associated diseases with A7H9F8

9 regional properties for A7H9F8

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 14 - 143 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 333 - 465 IPR001247-2
domain S1 domain 628 - 699 IPR003029
domain K Homology domain 561 - 626 IPR004087
domain K Homology domain, type 1 565 - 622 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 146 - 209 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 468 - 537 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 241 - 328 IPR015848
domain RNA-binding domain, S1 629 - 699 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPIQKTARV GAQEILLETG KVAKQAHGSV WVRMGDSIVL VTVVSAAEKK EGIDFFPLTV
70 80 90 100 110 120
DYQEKLFAAG RVPGSFFRRE GRPTEKETLT SRIVDRSCRP LFAEGYPNET QIIATVISFD
130 140 150 160 170 180
QENDTDVLAL TGASAALHLS DIPFNGPIAG VRVGRVNGQF VANPTLAQRA EADLDVIMAA
190 200 210 220 230 240
SRDAIVMVEG GAKEVSEQVM VDALLFGQAA VRELLDAQDA LRKATGDKPR RAFDPPKNDV
250 260 270 280 290 300
ALREKVKALT WEKVKEAYAR NEKHDRYGRL SEIKKELLQA LKEEAAGDAQ KLAAIALREK
310 320 330 340 350 360
EIKGYYEDVK YEYMRKMITD ERRRIGGRGE ADIRKITSEV GLLPRVHGSS LFTRGETQAL
370 380 390 400 410 420
VATTLGTAED EQRVEMLTGM VFKRFMLHYN FPPFSVGEVK FLRSPGRREI GHGALAERAL
430 440 450 460 470 480
RQVMPPEDKF PYTVRIVSDI MESNGSSSMA SVCGGCLSLM DAGVPIKAPV AGIAMGLIKE
490 500 510 520 530 540
GEKIAILSDI LGDEDHLGDM DFKVCGTAEG ITSIQMDIKI GGVTREILER ALAQAADGRK
550 560 570 580 590 600
HILGEMAKAI ATPRESISAY APRITTIKIR PERIKDIIGP GGKTIKDITA RTGTSINIED
610 620 630 640 650 660
DGSVSIASPS QDKVEAAIKM IRSLTQEAEI GKTYLGTVRK IAEFGAFVEL FPGTDGLIHI
670 680 690 700 710 720
SELSDKRVKS VSDVLSEGEE VLVKVISVDR AGKIRLSRKE ALAEAAGKKP EGAAETKGEP
AK