Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A7H220

Entry ID Method Resolution Chain Position Source
AF-A7H220-F1 Predicted AlphaFoldDB

No variants for A7H220

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7H220

No associated diseases with A7H220

4 regional properties for A7H220

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 122 - 314 IPR024953
domain Polyphosphate kinase N-terminal domain 8 - 111 IPR025198
domain Polyphosphate kinase C-terminal domain 2 495 - 660 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 323 - 488 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQTSPDMFIN RELSWLRFNS RVLDQCSKNL PLLEKLKFIA IYCTNLDEFY MIRVAGLKQL
70 80 90 100 110 120
FSAGVNASSS DEMTPLQQLK AIRKYLHQEK ELLEHYFNEI TSELEKENLF IKHYENLDEN
130 140 150 160 170 180
LKQKCDEYFF SNIFPVIVPI AVDATHPFPH LNNLSFSLAV KIFDKAHPEL VKFGMIRIPR
190 200 210 220 230 240
VLPRFYEVSA NIYVPIESIV HQHAEEIFPG YKLLASAAFR VTRNADMVIE EEEADDFMMI
250 260 270 280 290 300
LEQGLKLRRK GAFVRLQIQK DADEQIVEFL NTHMKIFHKD VYEYSILLNL PSLWQIAGNK
310 320 330 340 350 360
NFTHLLSPLY TPKTLPPFDE NLSIFDAVEK EDILIIQPFE SFDPVYKFIK EASKDPEVIS
370 380 390 400 410 420
IRMTLYRVEK NSNIVQALID AASDGKQVTV MVELKARFDE ENNLHWAKAL ENAGAHVIYG
430 440 450 460 470 480
ITGFKVHAKV SQVIRKQGDK LKFYMHLSTG NYNASSAKIY TDVSYFTSKA EFARDTTSFF
490 500 510 520 530 540
HILSGFSKNR RLQTLSMSPN QIKEKILEMI RIETSKKNKG VIVAKMNSLV DSDIIQALYE
550 560 570 580 590 600
ASMEGVKIDL IIRGICCLKP DEEYSKNIRV RSIIGKYLEH ARVFYFKHSE PNYFISSADW
610 620 630 640 650 660
MPRNLERRLE LMTPIYDERS KAKLAQFLRL QLSDNVLAYE LKNNGEYEKI PSSEKTIDSQ
670 680 690
QTLEEYVSKI YKTLKKDTDQ SRATHLASKL FKEN