A7GTS8
Gene name |
thiI |
Protein name |
Probable tRNA sulfurtransferase |
Names |
Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase |
Species |
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) |
KEGG Pathway |
bcy:Bcer98_3319 |
EC number |
2.8.1.4: Sulfurtransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7GTS8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7GTS8-F1 | Predicted | AlphaFoldDB |
No variants for A7GTS8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7GTS8 | |||||
No associated diseases with A7GTS8
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.1.4 | Sulfurtransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tRNA adenylyltransferase activity | Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1). |
| tRNA binding | Binding to a transfer RNA. |
| tRNA U4 sulfurtransferase | Catalyzes the reaction: ATP |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| thiamine biosynthetic process | +The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. |
| thiamine diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. |
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMKYDHILVR | YGEMTTKGKN | RSKFVSTLKD | NVKFKLKKFP | NIKINATHDR | MYIELNGEDH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAIAESLKDV | FGIHKFNLAM | KVPSELEEIK | KGALAAFLLI | KKPVKTFKIT | VHRSYKHFPM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QTMELLPEIG | GYVLENTEDI | MVDVHNPDVN | IRIEIRSGYS | YIMCDERMGA | GGLPVGVGGK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VMVLLSGGID | SPVAAYLTMK | RGVSVEAVHF | HSPPFTSERA | KQKVIDLAQE | LTKYCKRVTL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HLVPFTEVQK | TINKEIPSSY | TMTVMRRMMM | RITERIAEER | NALAITTGES | LGQVASQTLD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SMHTINEVTN | YPVLRPLITM | DKLEIIKIAN | EIGTYDISIR | PYEDCCTVFT | PANPATKPKR |
| 370 | 380 | 390 | 400 | ||
| EKASRFEAKY | DFTPLLEQAV | ANTETMVLQT | VDKAEEDQFE | DLF |