A7FJU4
Gene name |
pncB |
Protein name |
Nicotinate phosphoribosyltransferase |
Names |
NAPRTase |
Species |
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) |
KEGG Pathway |
ypi:YpsIP31758_2557 |
EC number |
6.3.4.21: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7FJU4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7FJU4-F1 | Predicted | AlphaFoldDB |
No variants for A7FJU4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7FJU4 | |||||
No associated diseases with A7FJU4
9 regional properties for A7FJU4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exoribonuclease, phosphorolytic domain 1 | 15 - 144 | IPR001247-1 |
| domain | Exoribonuclease, phosphorolytic domain 1 | 325 - 457 | IPR001247-2 |
| domain | S1 domain | 622 - 691 | IPR003029 |
| domain | K Homology domain | 553 - 618 | IPR004087 |
| domain | K Homology domain, type 1 | 557 - 613 | IPR004088 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 147 - 210 | IPR015847-1 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 460 - 528 | IPR015847-2 |
| domain | Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 248 - 321 | IPR015848 |
| domain | RNA-binding domain, S1 | 621 - 691 | IPR022967 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.21 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| nicotinate phosphoribosyltransferase activity | Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| NAD biosynthetic process | The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTQDASPILT | SLLDTDAYKL | HMQQAVFHHY | RHITVAAEFR | CRSDELLGVY | ADEIRHQVTL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MGQLALTSDE | FIYLSSLPFF | QDDYLHWLRD | FRFKPEQVSV | AVHDGKLDIR | IAGLWCEVIM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WEVPLLAVIS | EIVHRRRSTQ | VTTDQAVQQL | RTKLEQFNAL | SADIDITHFK | LMDFGTRRRF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SREIQHTVVS | TLKDEFPYLV | GTSNYDLART | LALAPVGTQA | HEWFQAHQQI | SPTLANSQRV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALQVWLDEYP | NQLGIALTDC | ITMDAFLRDF | DLAFANRYQG | LRHDSGDPIE | WGEKAIAHYE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KLGIDPMKKV | LVFSDNLDLE | KALFLYRHFY | QRIKLVFGIG | TRLTCDIPDV | KPLNIVIKLV |
| 370 | 380 | 390 | 400 | ||
| ECNDKPVAKL | SDSPGKTICQ | DPAFVDQLRK | AFALPLVKKA | S |