A7FFD1

PR
Gene name
aas
Protein name
Bifunctional protein Aas
Names
Species
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
KEGG Pathway
ypi:YpsIP31758_0975
EC number
2.3.1.40: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

606-678 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7FFD1

Entry ID Method Resolution Chain Position Source
AF-A7FFD1-F1 Predicted AlphaFoldDB

No variants for A7FFD1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7FFD1

No associated diseases with A7FFD1

4 regional properties for A7FFD1

Type Name Position InterPro Accession
domain AMP-dependent synthetase/ligase domain 231 - 619 IPR000873
domain Phospholipid/glycerol acyltransferase 24 - 140 IPR002123
conserved_site AMP-binding, conserved site 370 - 381 IPR020845
domain AMP-binding enzyme, C-terminal domain 630 - 701 IPR025110

Functions

Description
EC Number 2.3.1.40 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity Catalysis of the reaction: acyl- + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
long-chain fatty acid [acyl-carrier-protein] ligase activity Catalysis of the reaction: ATP + an acid

2 GO annotations of biological process

Name Definition
fatty acid metabolic process +The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAYRLLRALF RGLFRVTIDG VTDQFKHEKL IITPNHVSFL DGALLALFLP IKPVFAVYTS
70 80 90 100 110 120
ITDTWYMRWL KPYVDFVALD PTNPMAIKHL VRMVEQGRPV VIFPEGRITV TGSLMKIYDG
130 140 150 160 170 180
AAFVAAKSGA AVVPIRLDGP EFTHFGRLQG VLKTRWFPKI SIHVLPATTI PMPQAPRSRE
190 200 210 220 230 240
RRVLAGEHLH TIMMAARMAT VPRETLFEAL LSAQTRYGRF KPCIEDVSFK EDSYQTLLKK
250 260 270 280 290 300
TLGVSRILQR FTVPGEHVGM LLPNATITAA AIFGASLRGR IPALLNYTSG AKGLQSAIIA
310 320 330 340 350 360
ASLKTIVTSR QFLEKGKLTH LPEQVNEVNW VYLEDLKDTV TLTDKLWILF HLCFPRRAML
370 380 390 400 410 420
PQQADDSALI LFTSGSEGNP KGVVHSHASL LANVEQIRTI ADFTPRDRFM SSLPLFHAFG
430 440 450 460 470 480
LTVGLFTPLM TGSRVFLYPS PLHYRVVPEL VYDRNCTVLF GTSTFLGNYA RFAHPYDFAR
490 500 510 520 530 540
VRYVVAGAEK LAESTKQIWQ DKFGIRILEG YGVTECAPVV AINVPMAAKV NTVGRILPGM
550 560 570 580 590 600
EARLINVPGI AQGGRLQLRG PNIMRGYLRV ENPGVLEQPS AENAQGELDA NWYDTGDIVT
610 620 630 640 650 660
LDEQGFCAIR GRVKRFAKLA GEMVSLESVE QLAISLSPEG QHAAAAKTDS AKGEALVLFT
670 680 690 700 710
TDSEITRERL IKAARENGVP ELAVPRDIRV VKALPLLGSG KPDFVTLGKM AQDPEMSV