A7EXH9
Gene name |
sfh5 (SS1G_10044) |
Protein name |
Phosphatidylinositol transfer protein sfh5 |
Names |
PITP sfh5 |
Species |
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum) |
KEGG Pathway |
ssl:SS1G_10044 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7EXH9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7EXH9-F1 | Predicted | AlphaFoldDB |
No variants for A7EXH9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7EXH9 | |||||
No associated diseases with A7EXH9
6 regional properties for A7EXH9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 45 - 304 | IPR000719 |
| domain | SH2 domain | 422 - 503 | IPR000980 |
| domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | 46 - 300 | IPR001245 |
| active_site | Serine/threonine-protein kinase, active site | 163 - 175 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 51 - 72 | IPR017441 |
| domain | ShkA/ShkC, SH2 domain | 413 - 525 | IPR035844 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| phosphatidylinositol transfer activity | Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| Golgi to plasma membrane protein transport | The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. |
| regulation of exocytosis | Any process that modulates the frequency, rate or extent of exocytosis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAEVDTNIP | KENVPEEVVE | AKTTTTTTTM | EPEPLIVEDL | KSTTIESTPV | KIGDPTSNEQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IAREEPKPTI | TEPSTTKSVA | AEPTTEQHQE | TAVKLESVKE | ADAEAAARVE | STEDADGEKA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSTSQPSVSF | DKTTKTHDGS | PLSKFFSELP | EILKVAGHNE | MWGIILDPSE | DHVQTSIVLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFLRANTKDV | TKAKAQLTEA | LKWRKAMQPQ | KLLVDTEFDK | VKFGKLGYVT | SYPTSEGGKE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VITWNIYGAV | KDTKKTFSDV | PEFLRWRAAL | MELSIRELDL | ASATEKIPEN | GPDPYRMIQV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HDYLNVSFLR | MDPGIRAASK | ETIQTFSMAY | PELLKEKFFV | NVPMVMGWVF | TAMKIFLSAD |
| 370 | 380 | 390 | 400 | 410 | |
| TIKKFHPLSY | GSDLGAEIPG | IAEKLPKEYG | GKGEELESGF | TVKYSGDDVP | KSD |