A7A063

PR
Gene name
NFT1 (SCY_3473)
Protein name
ABC transporter NFT1
Names
New full-length MRP-type transporter 1
Species
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

378-461 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7A063

Entry ID Method Resolution Chain Position Source
AF-A7A063-F1 Predicted AlphaFoldDB

No variants for A7A063

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7A063

No associated diseases with A7A063

8 regional properties for A7A063

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 651 - 892 IPR003439-1
domain ABC transporter-like, ATP-binding domain 1285 - 1538 IPR003439-2
domain AAA+ ATPase domain 678 - 869 IPR003593-1
domain AAA+ ATPase domain 1311 - 1524 IPR003593-2
domain ABC transporter type 1, transmembrane domain 315 - 621 IPR011527-1
domain ABC transporter type 1, transmembrane domain 962 - 1251 IPR011527-2
conserved_site ABC transporter-like, conserved site 792 - 806 IPR017871-1
conserved_site ABC transporter-like, conserved site 1441 - 1455 IPR017871-2

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIKNGTCPFW ERDDLSECAR REYIEFKFPL FILLTGMIYA FCKVFRAFYL RRKNHTNEAP
70 80 90 100 110 120
EFEEQGNGNH EYARFSVLRL KSAWESRSFC NVNNRSTFDK FKKFIEGAFI VLQLTIHLYI
130 140 150 160 170 180
LSNMPMDNKK FFHQGFLVQM FLWILLLVVI TLRLISASQS FRWVLACKRD LWAVSFYSYA
190 200 210 220 230 240
SLFTLSILPL RSVFIGKIKD KIMVKYIISE TFIDLALLLL LSTSSIEGTR YSFLVENENK
250 260 270 280 290 300
KLPPAPTVFG LLTFSRIDRL IWKAYKHCLG NADIWDLDIN NKSIAILANF EMSSKKGRLL
310 320 330 340 350 360
PNIICYFKAV FISQLFLAFV SSFLNFVPSL LMPRILSYVN DPKSQSWNLV SLYVSSMLVS
370 380 390 400 410 420
KIIATTCRGQ GLFLGEKGTM QLRTVLISNI YSKTLRRTIL KDSTTSLQKN ASTSFEENPD
430 440 450 460 470 480
SSEAEPRKKS SRKDNSVNNV MSIDAFKVSE AMNTFYLACE AVFMTVTALM ILYSLLGWSA
490 500 510 520 530 540
FAGTFALLAM IPLNFWCATF YGNYQADQLI LTDKRTSGIS EALNSIRVIK LLAWENLFYQ
550 560 570 580 590 600
KIINVRDGEI RLLKKKATIF FLNHLIWFFG PTLVSAITFS VFIKFQNQTL TPTIAFTALS
610 620 630 640 650 660
LFAILRTPMD QIASTVSLLI QSFISLERIQ DYLNEPETRK YEILEQSNTK FGFEDASMEW
670 680 690 700 710 720
EAAETSFKLK NISIDFKLNS LNAIIGPTGS GKSSLLLGLL GELNLLSGKI YVPTVESRDD
730 740 750 760 770 780
LEIGKDGMTN SMAYCSQTPW LISGTIKDNV VFGEIFNKQK FDDVMKSCCL DKDIKAMTAG
790 800 810 820 830 840
IRTDVGDGGF SLSGGQQQRI ALARAIYSSS RYLILDDCLS AVDPETALYI YEECLCGPMM
850 860 870 880 890 900
KGRTCIITSH NISLVTKRAD WLVILDRGEV KSQGKPSDLI KSNEFLRESI NNDSKNTTHN
910 920 930 940 950 960
QIDLKRSTTS KKTKNGDPEG ENSQDEVCAE VENFEETKME GSVKFSAYKW LADYFGGLGV
970 980 990 1000 1010 1020
VFVFTSSAIL IHGITLSQGF WLRYWLETGS SGSKSTWLYR IVEGHSNIYF ILTYIVIGFV
1030 1040 1050 1060 1070 1080
SSFLTSGKVW IAIISGTNVT KKIFAKLLSS ILYAKLRFHN VTPTGRIMNR FSKDMDIIDQ
1090 1100 1110 1120 1130 1140
QLIPNFEGLS YSVVVCLWII LLIGYVTPQF LLFAIPLCAL YYTVCTLYLR ASRELKRIDN
1150 1160 1170 1180 1190 1200
INISPIHQLF AEAIKGVTTI RALADERRFI TQSLVAIDRS NAPFFYLNMA TEWITYRVDI
1210 1220 1230 1240 1250 1260
IGTLVLFSSS VMIIMKASYL DAGLAGILLS NAFSFTETAQ WIIKVFSSVE LLMSSVERIK
1270 1280 1290 1300 1310 1320
EYTDIPSESN GYISPPANWP QTGDVELKNL SLRYSPHSSK ALDNVSFKVK AGTKVGIVGR
1330 1340 1350 1360 1370 1380
TGAGKSSIIA AIYRLSDWEN GTIIIDNKDI KHIPLERLRN SISCIPQDPT LFDGTVRSNL
1390 1400 1410 1420 1430 1440
DPFDRYSDVQ IYGVLSKVGL IEECDELSLI SEQEQPNFSS HKLRNRFIDL NTVVKSGGSN
1450 1460 1470 1480 1490 1500
LSQGQRQLLC LARSMLGARN IMLIDEATAS IDYISDAKIQ KTIRETMKNT TILTIAHRLR
1510 1520 1530 1540 1550
SVIDYDKILV MEMGRVKEYD HPYTLISDRN TIFYRLCRQS GEFENLFELA KVSFDNKR