A6ZP88

PR
Gene name
CLP1
Protein name
mRNA cleavage and polyadenylation factor CLP1
Names
Species
Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6ZP88

Entry ID Method Resolution Chain Position Source
AF-A6ZP88-F1 Predicted AlphaFoldDB

No variants for A6ZP88

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6ZP88

No associated diseases with A6ZP88

3 regional properties for A6ZP88

Type Name Position InterPro Accession
domain Pre-mRNA cleavage complex subunit Clp1, C-terminal 341 - 445 IPR010655
domain Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain 130 - 335 IPR032319
domain Clp1, N-terminal beta-sandwich domain 28 - 118 IPR032324

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mRNA cleavage factor complex Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.

1 GO annotations of biological process

Name Definition
mRNA 3'-end processing Any process involved in forming the mature 3' end of an mRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASLPGIDEH TTSEELITGD NEWHKLVIPK GSDWQIDLKA EGKLIVKVNS GIVEIFGTEL
70 80 90 100 110 120
AVDDEYTFQN WKFPIYAVEE TELLWKCPDL TTNTITVKPN HTMKYIYNLH FMLEKIRMSN
130 140 150 160 170 180
FEGPRVVIVG GSQTGKTSLS RTLCSYALKF NAYQPLYINL DPQQPIFTVP GCISATPISD
190 200 210 220 230 240
ILDAQLPTWG QSLTSGATLL HNKQPMVKNF GLERINENKD LYLECISQLG QVVGQRLHLD
250 260 270 280 290 300
PQVRRSGCIV DTPSISQLDE NLAELHHIIE KLNVNIMLVL CSETDPLWEK VKKTFGPELG
310 320 330 340 350 360
NNNIFFIPKL DGVSAVDDVY KRSLQRTSIR EYFYGSLDTA LSPYAIGVDY EDLTIWKPSN
370 380 390 400 410 420
VFDNEVGRVE LFPVTITPSN LQHAIIAITF AERRADQATV IKSPILGFAL ITEVNEKRRK
430 440
LRVLLPVPGR LPSKAMILTS YRYLE