Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6ZLF4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6ZLF4-F1 | Predicted | AlphaFoldDB |
No variants for A6ZLF4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6ZLF4 | |||||
No associated diseases with A6ZLF4
4 regional properties for A6ZLF4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CBS domain | 118 - 167 | IPR000644-1 |
| domain | CBS domain | 198 - 256 | IPR000644-2 |
| domain | CBS domain | 283 - 342 | IPR000644-3 |
| domain | CBS domain | 368 - 415 | IPR000644-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to glucose starvation | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. |
| regulation of mitotic metaphase/anaphase transition | Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASTSNTFPP | SQSNSSNNLP | TSRHASIVEM | LSTPPLLPHV | QVNDTDDKEQ | PEESTPPTAT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AAAPGPGCAA | TPAPLRDEKP | QFKLSAVPMT | QTPSQCLSCV | HAQKWQHIPL | SQLIEQNKLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FVPGSISVEE | AFNTLIKYHL | NSIPVESFPG | DMNCFTFDYN | DLNSYLLLVL | NKITVSNKQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TADCQNGKPV | PVGEMVKLTP | KNPFYKLPEN | ESLSTVMGIL | GSGVHRVAIT | NEEMTKVKGI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSQRRLIKYL | WDNARSFTSL | EPLLNSSLQD | LHIGVLNIQS | KPTSRQSRVI | SIQGEEPLIM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GLYKMHVERI | SSIAVIDKQG | NLLGNISVTD | VKHVTRTSQY | PLLHKTCRHF | ISVILNSRGL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ETGKDSFPIF | HVYPSSSLAR | TLAKLVATKS | HRLWIVQPPE | SSTSASSTNL | TAANTAANAV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SATAQSSANG | ATPMSKSSSS | TSLNSHSPLM | TAMEDPPSPR | SSAIAIPPPS | PASSTNTPNL |
| 490 | 500 | 510 | 520 | ||
| FEKEYRTGKL | IGVVSLTDII | NLLARKQTGN | KEVDPQSARR | QRGSIAM |