A6WZQ6

PR
Gene name
murG
Protein name
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Names
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Species
Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) (Ochrobactrum anthropi)
KEGG Pathway
oan:Oant_1744
EC number
2.4.1.227: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

292-368 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6WZQ6

Entry ID Method Resolution Chain Position Source
AF-A6WZQ6-F1 Predicted AlphaFoldDB

No variants for A6WZQ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6WZQ6

No associated diseases with A6WZQ6

2 regional properties for A6WZQ6

Type Name Position InterPro Accession
domain Glycosyltransferase family 28, N-terminal domain 6 - 141 IPR004276
domain Glycosyl transferase, family 28, C-terminal 187 - 351 IPR007235

Functions

Description
EC Number 2.4.1.227 Hexosyltransferases
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.

7 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
lipid glycosylation Covalent attachment of a glycosyl residue to a lipid molecule.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVKGVIVLAA GGTGGHLFPA EALAHELKAR GWDVHLATDA RAQRFAGAFA EDHVHVIRSA
70 80 90 100 110 120
TIAGRNPIAL LKTFWSLWQG NLDSRKLFRR LKPKLVAGFG GYPTLPPLYA ASNMNIPTMV
130 140 150 160 170 180
HEQNAVMGRA NKGLAGRVKA IAGGFLPETG GVYAEKTVTT GNPVRPPVLA AAETSYKPVK
190 200 210 220 230 240
ADERFRLLVF GGSQGAQFFS TAIPAAVALL PDRDRARLLI TQQARKEDEA AVREAYKKLG
250 260 270 280 290 300
VPADVAPFFN DMPARMADAQ FVISRSGAST VSEITVIGRP AMLVPFPHAL DHDQAANAAA
310 320 330 340 350 360
LAAVGGGEVV RQSELSPERL AEILQAAMNE PQRLEAQAKA AKSVGKPDAA RLLADLAEAI
370
AAGKSVQEFK EGTRP