A6WLP6

PR
Gene name
lpxH
Protein name
UDP-2,3-diacylglucosamine hydrolase
Names
UDP-2,3-diacylglucosamine diphosphatase
Species
Shewanella baltica (strain OS185)
KEGG Pathway
sbm:Shew185_1588
EC number
3.6.1.54: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

122-195 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6WLP6

Entry ID Method Resolution Chain Position Source
AF-A6WLP6-F1 Predicted AlphaFoldDB

No variants for A6WLP6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6WLP6

No associated diseases with A6WLP6

1 regional properties for A6WLP6

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 1 - 198 IPR004843

Functions

Description
EC Number 3.6.1.54 In phosphorus-containing anhydrides
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
extrinsic component of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

2 GO annotations of molecular function

Name Definition
manganese ion binding Binding to a manganese ion (Mn).
UDP-2,3-diacylglucosamine hydrolase activity Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.

1 GO annotations of biological process

Name Definition
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRTLFIGDLH LSADRLDITQ AFTRFLDTEL DDADALYILG DLFEVWVGDD IALPFALELA
70 80 90 100 110 120
EKLKQVSQKL PVYFIHGNRD FMLGKQFARA AGMQILPEVT CLNLYGVETV ILHGDSLCTL
130 140 150 160 170 180
DKAYQRFRKL RSLSLARWLY GCLSKKTRQG IADKIRSNSK SSNQQKSYTI MDVEPNAVDA
190 200 210 220 230
LFAKTHTKHM IHGHTHRPAI HLLANDCQRI VVGDWYEQGS VLSVSAEGIN LQSLPFEHTT