A6W7G7

PR
Gene name
atpA
Protein name
ATP synthase subunit alpha
Names
ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha
Species
Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
KEGG Pathway
kra:Krad_1268
EC number
7.1.2.2: Hydron translocation linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

472-552 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6W7G7

Entry ID Method Resolution Chain Position Source
AF-A6W7G7-F1 Predicted AlphaFoldDB

No variants for A6W7G7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6W7G7

No associated diseases with A6W7G7

5 regional properties for A6W7G7

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 153 - 376 IPR000194
domain ATP synthase, alpha subunit, C-terminal 383 - 512 IPR000793
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 30 - 96 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 367 - 376 IPR020003
domain ATP synthase, F1 complex, alpha subunit nucleotide-binding domain 98 - 379 IPR033732

Functions

Description
EC Number 7.1.2.2 Hydron translocation linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
proton-transporting ATP synthase complex, catalytic core F(1) The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
proton-transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAELTIRPEE IRDALDAFVA SYDPGTAARE EVGRVTDAGD GIAHVEGLPS VMANELLRFQ
70 80 90 100 110 120
DGTLGLAQNL DVRDIGVVVL GDYAGIEEGQ EVHRTGEVLS VPVGDNFLGR VVDPLGAPID
130 140 150 160 170 180
GLGPIEAETR RALELQAPSV MQRQEVREPL QTGIKAIDAM IPVGRGQRQL IIGDRQTGKS
190 200 210 220 230 240
AIAIDTIINQ KANWESGDPK QQVRCIYVAI GQKGSTIAAV RRSLEEAGAM EYTTIVAAPA
250 260 270 280 290 300
SDPAGFKYLA PYTGSSIGQH WMYGGKHVLI VFDDLSKQAE AYRAVSLLLR RPPGREAYPG
310 320 330 340 350 360
DVFYLHSRLL ERCAKLSDEL GGGSMTGLPF IETKGNDVSA YIPTNVISIT DGQIFLQSDL
370 380 390 400 410 420
FNANQRPAID VGISVSRVGG AAQTKAIKGI SGTLKLDLAQ FRAMEAFAMF ASDLDQASRN
430 440 450 460 470 480
QLARGARLVE LLKQPQYTPF SLEEQVVSIW AGTTGQLDSV EVSDISRFER EFLEYVKRNH
490 500 510 520 530 540
AGVMQGIRET KQFSDGAKDE LKKAVDAFKP QFSGGSKGSN VPKDVDAGAT DADDISQEKI
550
TTRKGGATAA RG