A6VFU0
Gene name |
trpF |
Protein name |
N-(5'-phosphoribosyl)anthranilate isomerase |
Names |
PRAI |
Species |
Methanococcus maripaludis (strain C7 / ATCC BAA-1331) |
KEGG Pathway |
mmz:MmarC7_0246 |
EC number |
5.3.1.24: Interconverting aldoses and ketoses |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6VFU0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6VFU0-F1 | Predicted | AlphaFoldDB |
No variants for A6VFU0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6VFU0 | |||||
No associated diseases with A6VFU0
1 regional properties for A6VFU0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | N-(5'phosphoribosyl) anthranilate isomerase (PRAI) domain | 1 - 206 | IPR001240 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.3.1.24 | Interconverting aldoses and ketoses |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphoribosylanthranilate isomerase activity | Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tryptophan biosynthetic process | The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFIKICGIKT | PEELEIVESY | GNATGVILEC | ASKRRIGLET | AKNLVNLSNI | PVFAVSTTSE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLVWENIIKL | TNTNYLQMHS | DIDQKTIDFI | KNEYGCFIMK | SFKIPETSES | PEIDAEKIIS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DIETYEVDRI | LLDTGKGCGQ | THDHRISQII | AKKFDIILAG | GLDPDNVFDI | VKNVKPFGVD |
| 190 | 200 | ||||
| VSSGVEANNS | KDEELIKRFC | ENVKSVKL |