A6V7H8
Gene name |
gpsA |
Protein name |
Glycerol-3-phosphate dehydrogenase [NAD(P)+] |
Names |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase |
Species |
Pseudomonas aeruginosa (strain PA7) |
KEGG Pathway |
pap:PSPA7_3659 |
EC number |
1.1.1.94: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6V7H8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6V7H8-F1 | Predicted | AlphaFoldDB |
No variants for A6V7H8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6V7H8 | |||||
No associated diseases with A6V7H8
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.94 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| glycerol-3-phosphate dehydrogenase complex | An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycerol-3-phosphate dehydrogenase [NAD+] activity | Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+. |
| NAD binding | Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| glycerol-3-phosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol. |
| glycerol-3-phosphate catabolic process | The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol. |
| glycerophospholipid metabolic process | The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. |
| phospholipid biosynthetic process | The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEQQPIAVL | GGGSFGTAIA | NLLAENGQAV | RQWMRDPEQA | EAIRSRRENP | RYLKGVKVHP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GVEPVTDLER | TLADCQLIFV | ALPSSALRKV | LQPHQLALTD | KLLVSLTKGI | EAHTFKLMSE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILEEIAPQAR | IGVISGPNLA | REIAEHELTA | TVVASEDDEL | CARVQAALHG | RTFRVYASRD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RFGVELGGAL | KNVYAIMAGL | AAAMDMGENT | RSMLITRALA | EMTRFAVKLG | ANPMTFLGLA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GVGDLIVTCS | SPKSRNYQVG | HALGEGLSLE | QAVSRLGETA | EGVNTLRVLK | EKSDEMQVYM |
| 310 | 320 | 330 | |||
| PLVAGLHAIL | FEGRTLAQVI | QLLMRGEPKT | DVDFIPTTGF |