A6V2N1

PR
Gene name
glk
Protein name
Glucokinase
Names
Glucose kinase
Species
Pseudomonas aeruginosa (strain PA7)
KEGG Pathway
pap:PSPA7_1935
EC number
2.7.1.2: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

297-339 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6V2N1

Entry ID Method Resolution Chain Position Source
AF-A6V2N1-F1 Predicted AlphaFoldDB

No variants for A6V2N1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6V2N1

No associated diseases with A6V2N1

5 regional properties for A6V2N1

Type Name Position InterPro Accession
domain Alpha-D-phosphohexomutase, C-terminal 373 - 443 IPR005843
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 3 - 134 IPR005844
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 166 - 253 IPR005845
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 257 - 366 IPR005846
conserved_site Alpha-D-phosphohexomutase, conserved site 95 - 104 IPR016066

Functions

Description
EC Number 2.7.1.2 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glucokinase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
glucose binding Binding to D- or L-enantiomers of glucose.

1 GO annotations of biological process

Name Definition
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNNDKNGSSG GLALIGDIGG TNARFALWRG QRLESIAVLA CADYPRPELA VRDYLARVGE
70 80 90 100 110 120
SLANIDSVCL ACAGPVGAGD FRFTNNHWSI NRAAFREELG LDHLLLVNDF STMAWAASRL
130 140 150 160 170 180
GADELVQVRP GSAQADRARL IIGPGTGLGV GSLLPLGEGR WEVLPCEGGH VDLPVTSARD
190 200 210 220 230 240
FAVWESLRER YGHVSAERVL SGNGLLALYE ISCALDGIPV RATSAAEVGA LALAGDAQAD
250 260 270 280 290 300
AVLEHFFLWL ARVAGNAALT VGALGGVYIT GGIVPRFRER FLASGFAGAF ASRGKTSGAY
310 320 330
LQDVPVWIMT AEHPGLLGAG VALQQALDAE SRTGVRATA