A6UQB4

PR
Gene name
pfdA
Protein name
Prefoldin subunit alpha
Names
GimC subunit alpha
Species
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
KEGG Pathway
mvn:Mevan_0780
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6UQB4

Entry ID Method Resolution Chain Position Source
AF-A6UQB4-F1 Predicted AlphaFoldDB

No variants for A6UQB4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6UQB4

No associated diseases with A6UQB4

1 regional properties for A6UQB4

Type Name Position InterPro Accession
domain Phosphofructokinase domain 3 - 275 IPR000023

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.

1 GO annotations of molecular function

Name Definition
unfolded protein binding Binding to an unfolded protein.

1 GO annotations of biological process

Name Definition
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNEELQNQFM ALDVYNQQVQ KLQEELSNID LMIMELVRAI ESMESLKTSG EIMLPLGAGS
70 80 90 100 110 120
FVKADVKNPE KIILSVGVDV LLEKDVEEVI LDFKNSLDEL EKTKELITTQ IQKTSKEVTR
130 140
IRGELEKRAA AIEKQSQTKR GHSGSN