A6TUN0

PR
Gene name
secA2
Protein name
Protein translocase subunit SecA 2
Names
Species
Alkaliphilus metalliredigens (strain QYMF)
KEGG Pathway
amt:Amet_3779
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

704-780 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6TUN0

Entry ID Method Resolution Chain Position Source
AF-A6TUN0-F1 Predicted AlphaFoldDB

No variants for A6TUN0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6TUN0

No associated diseases with A6TUN0

9 regional properties for A6TUN0

Type Name Position InterPro Accession
domain Helicase, C-terminal 419 - 588 IPR001650
domain SecA DEAD-like, N-terminal 8 - 387 IPR011115
domain SecA Wing/Scaffold 581 - 631 IPR011116-1
domain SecA Wing/Scaffold 657 - 728 IPR011116-2
domain SecA, preprotein cross-linking domain 231 - 343 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 92 - 249 IPR014001
domain SecA motor DEAD 8 - 596 IPR014018
conserved_site SecA conserved site 485 - 500 IPR020937
domain SecA, C-terminal helicase domain 405 - 552 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKNISSVSK RFENFKNKEV YDIELYKKTV EEINNINYKN ASDTELREIS ENLKNKVKEG
70 80 90 100 110 120
IPLDEVLIQA FTLVKEVAGR VVGMTPYDVQ KMAAIALHQG KVVEMQTGEG KTLSAVMPAY
130 140 150 160 170 180
LNALSGKGVH ILTFNDYLAE RDFRWMGPIY KFLGLSCGFV KENMNLEERR KAYLKDITYV
190 200 210 220 230 240
TARESGFDYL RDFLCTEVKD LVHRPFNYAI LDEADSILID EARIPLVIAG NVSEEGFNYD
250 260 270 280 290 300
HLIEIVRSLK PNVDYEIDQH HHNVVLTEKG LIKIEKVSGC GNLYASENLQ LLTRLNCVLH
310 320 330 340 350 360
AEILLKKEID YIVRKGKIEI IDEFTGRVAD KRHWPDSLHE AVEAKEGLVS ETKGRIMGSI
370 380 390 400 410 420
ALQYFLKLYP KLAGMTGTAI SVMNELDRMY QLKVVLIPTN KPCIRKDYPD KIFTCKEIKE
430 440 450 460 470 480
KTLILEIKNI NATGQPILIG TSSVEESERI ATTLNTEGIK CNVLNAKNDW EEAKIIAEAG
490 500 510 520 530 540
KYGAVTVSTN MAGRGIDIKL GGEKELDRKK VVTKGGLYVI GTSRHESSRI DNQLRGRAGR
550 560 570 580 590 600
QGDPGESKFF ISLEDDLIKK YEIDKMIPQE YYTQKQSESL DNTMINRKIN SGQRIVEGYN
610 620 630 640 650 660
SDIRKQLWEY SYVIEEQRRI IHQKRHEILV DREPLSLLSN KCPVLYDRYL DLVGKDVLYK
670 680 690 700 710 720
VEKQITLFHI NKCWAEYLEY VSYIREGIHL VVIGKENPLH RFQSITIEAF NDMLDNIEKD
730 740 750 760 770 780
IIETFIKANV TKDGVDIEKE KLKGPSSTWT YLISDSPNQF SRLPFIVKGV LFSLRSISNG
790
IVRKVQETIN VVIQK