Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A6TSK9

Entry ID Method Resolution Chain Position Source
AF-A6TSK9-F1 Predicted AlphaFoldDB

No variants for A6TSK9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6TSK9

No associated diseases with A6TSK9

3 regional properties for A6TSK9

Type Name Position InterPro Accession
conserved_site GTP cyclohydrolase I, conserved site 96 - 112 IPR018234-1
conserved_site GTP cyclohydrolase I, conserved site 144 - 154 IPR018234-2
domain GTP cyclohydrolase I domain 38 - 216 IPR020602

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Membrane raft ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane raft Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEFIPFIIL IGVAFVILSI ILSFVPVGLW ITAQFSGVKV GIFTLVGMRF RRVQPIRIIN
70 80 90 100 110 120
PLIKATKAGI DINIDKLEAH YLAGGDVNTL VDALIAAQRA EINLPFERAA AIDLAGRQVL
130 140 150 160 170 180
EAVQVSVNPK VIETPKIAAV AKDGIEVMAR ARVTVRANIE RLVGGAGEET IIARVGEGIV
190 200 210 220 230 240
TTVGSATTHK HVLENPDMIS KTVLSKGLDA GTAYEILSID IADIDIGRNI GAQLQTDQAD
250 260 270 280 290 300
ADKRIAQAKA EERRAMAVAK EQEMKAAVQE MRAKVVEAEA EVPKALATAL REGKMGVMDY
310 320
YNMKNIMADT DMRDSISKVA PNEKKYEEE