A6THZ0
Gene name |
prfC |
Protein name |
Peptide chain release factor 3 |
Names |
RF-3 |
Species |
Klebsiella pneumoniae subsp pneumoniae (strain ATCC 700721 / MGH 78578) |
KEGG Pathway |
kpn:KPN_04831 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6THZ0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6THZ0-F1 | Predicted | AlphaFoldDB |
No variants for A6THZ0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6THZ0 | |||||
No associated diseases with A6THZ0
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation release factor activity, codon specific | A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of translational termination | Any process that modulates the frequency, rate or extent of translational termination. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTLSPYLQEV | AKRRTFAIIS | HPDAGKTTIT | EKVLLFGQAI | QTAGTVKGRG | SSQHAKSDWM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EMEKQRGISI | TTSVMQFPYH | DCLVNLLDTP | GHEDFSEDTY | RTLTAVDCCL | MVIDAAKGVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DRTRKLMEVT | RLRDTPILTF | MNKLDRDIRD | PMELLDEVEN | ELKIGCAPIT | WPIGCGKLFK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVYHLYKDET | YLYQTGKGHT | IQEVRIVKGL | NNPDLDAAVG | EDLAQQLRDE | LELVQGASNE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FDKDLFLAGE | ITPVFFGTAL | GNFGVDHMLD | GLVEWAPAPM | PRNTDTREVT | ATEEKFTGFV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FKIQANMDPK | HRDRVAFMRV | VSGKYEKGMK | LRQVRIGKDV | VISDALTFMA | GDRSHVEEAY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PGDIIGLHNH | GTIQIGDTFT | QGEMMKFTGI | PNFAPELFRR | IRLKDPLKQK | QLLKGLVQLS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEGAVQVFRP | IANNDLIVGA | VGVLQFDVVV | ARLKSEYNVE | AIYESVNVAT | ARWVESTDVK |
| 490 | 500 | 510 | 520 | ||
| KFEEFKRKNE | VQLALDGGDN | LTYIAPTMVN | LNLTQERYPD | VVFRKTREH |