A6TEY9

PR
Gene name
kefB
Protein name
Glutathione-regulated potassium-efflux system protein KefB
Names
K(+)/H(+) antiporter
Species
Klebsiella pneumoniae subsp pneumoniae (strain ATCC 700721 / MGH 78578)
KEGG Pathway
kpn:KPN_03736
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

350-422 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6TEY9

Entry ID Method Resolution Chain Position Source
AF-A6TEY9-F1 Predicted AlphaFoldDB

No variants for A6TEY9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6TEY9

No associated diseases with A6TEY9

3 regional properties for A6TEY9

Type Name Position InterPro Accession
domain Regulator of K+ conductance, N-terminal 402 - 524 IPR003148
domain K+/H+ exchanger 14 - 283 IPR004771
domain Cation/H+ exchanger 12 - 373 IPR006153

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
glutathione-regulated potassium exporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
solute:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGSDLLLAG VLFLFAAVIA VPLASRLGIG AVLGYLLAGI AIGPWGLGFI SDVDEILHFS
70 80 90 100 110 120
ELGVVFLMFI IGLELNPAKL WRLRSSIFGV GAAQVMLSAA ILGGLLMTTG FSWQAAVVGG
130 140 150 160 170 180
IGLAMSSTAM ALQLMREKGM SRSEAGQLGF SVLLFQDLAV IPALALVPLL AGSADEHVNW
190 200 210 220 230 240
LTVGMKVLAF AGMLIGGRYL LRPVFRFIAS SGVREVFTAA TLLLVLGSAL FMEALGLSMA
250 260 270 280 290 300
LGTFIAGVLL AESEYRHELE IAIDPFKGLL LGLFFISVGM ALNLGVLYTH LLWVAVSVAV
310 320 330 340 350 360
LVAVKMLVLY LLARLYGLRS SERMQFAGVL SQGGEFAFVL FSLPASQRLF LHDQMALLLV
370 380 390 400 410 420
AVTLSMMTTP LLMKGIDKLL SRRLNPADDT GEAPWVEDDK PQVIIVGFGR FGQVIGRLLM
430 440 450 460 470 480
ANKMRITVLE RDISAVNLMR NYGYKVYFGD ATQLELLRSA GAEEAQSIVI TCNEPEDTMR
490 500 510 520 530 540
LVEMCQQHFP HLHILARARG RVEAHELLQA GVTQFSRETF SSALELGRKA LITLGMHPHQ
550 560 570 580 590 600
AQRAQLHFRR LDMRMLRELM PVHTDTVQIS RVREARRELE EIFQREMQKE SRQLDGWDEF
E