A6TBV5

PR
Gene name
menC
Protein name
o-succinylbenzoate synthase
Names
Species
Klebsiella pneumoniae subsp pneumoniae (strain ATCC 700721 / MGH 78578)
KEGG Pathway
kpn:KPN_02659
EC number
4.2.1.113: Hydro-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

50-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6TBV5

Entry ID Method Resolution Chain Position Source
AF-A6TBV5-F1 Predicted AlphaFoldDB

No variants for A6TBV5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6TBV5

No associated diseases with A6TBV5

2 regional properties for A6TBV5

Type Name Position InterPro Accession
domain Mandelate racemase/muconate lactonizing enzyme, C-terminal 115 - 210 IPR013342
domain Enolase C-terminal domain-like 122 - 282 IPR029065

Functions

Description
EC Number 4.2.1.113 Hydro-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
O-succinylbenzoate synthase activity Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.

1 GO annotations of biological process

Name Definition
menaquinone biosynthetic process The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRVSQVYRWQ IPMDAGVVLR ERRLKTRDGL FIRLQEGERE GWGEISPLPG FSVETLEEAQ
70 80 90 100 110 120
MALLAWAQAW RDGAEPPLPT QPSVAFGISC AQAELGGELP QAADYRAAPL CSGDPDELFA
130 140 150 160 170 180
RLAAMPGEKV AKVKVGLWEA VRDGMVVNLL LEAIPDLQLR LDANRAWTPL KAQQFAKYVN
190 200 210 220 230 240
PAYRQRIAFL EEPCKTREDS RAFSRETGIA IAWDESLREA DFRFVAEPGV RAVVIKPTLT
250 260 270 280 290 300
GSLQKVQQQV AAAHALGLSV VISSSIESSL GLTQLARIAA WLTPQTIPGL DTLSLMGAQL
310 320
VRPWPESALP VLNIDALEPL L