A6TB47
Gene name |
otsA |
Protein name |
Trehalose-6-phosphate synthase |
Names |
TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase |
Species |
Klebsiella pneumoniae subsp pneumoniae (strain ATCC 700721 / MGH 78578) |
KEGG Pathway |
kpn:KPN_02392 |
EC number |
2.4.1.15: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6TB47
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6TB47-F1 | Predicted | AlphaFoldDB |
No variants for A6TB47
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6TB47 | |||||
No associated diseases with A6TB47
No regional properties for A6TB47
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A6TB47 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.15 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity | Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| trehalose biosynthetic process | The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSRLVVVSNR | IALPDDKKSS | AGGLAVGILG | ALRAAGGLWF | GWSGEIGDDQ | QPLKQVSRGN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ISWASFNLNE | RDHDEYYNQF | SNAVLWPAFH | YRLDLVSFQR | EAWEGYLRVN | AMLADKLLPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IEPDDTLWIH | DYHLLPFASE | LRKRGVNNRI | GFFLHIPFPT | PEIFNALPPH | AELLEQLCDY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DLLGFQTESD | RTAFLDSIAM | QTRLSDLGDK | RYQAWGKAFS | TEVYPIGIDP | DEITRNAKGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LPPKLAQLKN | ELKNVKNIFS | VERLDYSKGL | PERFLAYETL | LEKYPQHHGK | IRYTQIAPTS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RGDVQAYQDI | RHQLETAAGR | INGQFGQLGW | TPLYYLNQHF | DRKLLMKVFR | YSDVGLVTPL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RDGMNLVAKE | YVAAQDPDNP | GVLVLSQFAG | AAQELTSALI | VNPYDRDEVA | AALDRALSMP |
| 430 | 440 | 450 | 460 | 470 | |
| LAERIARHSA | MLDVIRENDI | HNWQARFVED | LQHISPRSEE | SRLRGKIATF | PKLA |