A6SI59
Gene name |
mcr1 (BC1G_12441) |
Protein name |
NADH-cytochrome b5 reductase 2 |
Names |
Mitochondrial cytochrome b reductase |
Species |
Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) |
KEGG Pathway |
bfu:BCIN_05g01380 |
EC number |
1.6.2.2: With a heme protein as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6SI59
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6SI59-F1 | Predicted | AlphaFoldDB |
No variants for A6SI59
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6SI59 | |||||
No associated diseases with A6SI59
6 regional properties for A6SI59
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 454 - 623 | IPR000795 |
| domain | Small GTP-binding protein domain | 457 - 613 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 1 - 50 | IPR006847-1 |
| domain | Translation initiation factor IF-2, N-terminal | 374 - 425 | IPR006847-2 |
| domain | Translation initiation factor IF- 2, domain 3 | 729 - 844 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 629 - 724 | IPR044145 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.2.2 | With a heme protein as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytochrome-b5 reductase activity, acting on NAD(P)H | Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFARQAIRAA | QPLKSQYRRY | ATESTSGGGS | NAALYAGLAA | AAGAGAYYFL | NQGDNAAKVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DAAKDAEAKA | KEAVGQGKSK | VEGAVGKAAF | TGGDQGFISL | KLDSVENINH | NTKKFRFELP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESDQVSGLQV | ASALLTKFKG | PEMQKPAIRP | YTPTSDESEQ | GFIDLLVKKY | PNGVMSEHMH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DMVPGQRLDF | KGPIPKYPWS | ANKHDHIALI | AGGTGITPMY | QLARAIFNNP | ADKTKVTLVF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANVTEEDILL | KREFEDLENT | YPQRFRAFYV | LDNPPKSWSG | GKGFVNKELL | KTVLPEPKTE |
| 310 | 320 | 330 | 340 | ||
| NVKVFVCGPP | GMYKAISGPK | VSPSDQGELA | GILKELGYSK | EQVYKF |