A6S8E7
Gene name |
trm8 (BC1G_09638) |
Protein name |
tRNA (guanine-N(7)-)-methyltransferase |
Names |
Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase |
Species |
Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) |
KEGG Pathway |
bfu:BCIN_11g00460 |
EC number |
2.1.1.33: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6S8E7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6S8E7-F1 | Predicted | AlphaFoldDB |
No variants for A6S8E7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6S8E7 | |||||
No associated diseases with A6S8E7
No regional properties for A6S8E7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A6S8E7 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.33 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| tRNA (m7G46) methyltransferase complex | A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat). |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (guanine-N7-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. |
| tRNA binding | Binding to a transfer RNA. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGPPNKKQK | REDYRTAREN | GEESKELPKK | KFYRQRAHAN | PFSDHRLAYP | ASPAQMDWAS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HYPAYAESAA | ASEGTEEPST | GSDSSSLKKL | KQDVEVADIG | CGFGGLTVAL | APKLPNSLIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GMEIRAQVTE | YVQERIKALR | VQEKESGLFQ | NASCIRANTM | KFMPNFFKKH | QLSKIFLCFP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DPHFKARKHK | ARIVSTTLAA | EYAYVVRPGG | IIYTITDVED | LHNWMVTHFN | AHPTFERVAE |
| 250 | 260 | 270 | 280 | ||
| EEQEADECVN | IMRTETEEGK | KVTRNNGPKF | VALFKRLEDP | PW |