A6RBC5

PR
Gene name
MIC60 (HCAG_06263)
Protein name
MICOS complex subunit MIC60
Names
Mitofilin
Species
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
KEGG Pathway
aje:HCAG_06263
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

11-123 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6RBC5

Entry ID Method Resolution Chain Position Source
AF-A6RBC5-F1 Predicted AlphaFoldDB

No variants for A6RBC5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6RBC5

No associated diseases with A6RBC5

No regional properties for A6RBC5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A6RBC5

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAMYLKSQAV LTLIPQRYHA LARKSNAGRR CSLTPNSATA SQFFQKAASS TSTKPPGPSD
70 80 90 100 110 120
ADVRSPASPS SRSSLRPESI PKPPQSPPVQ GQTSPGSEVL PPDHESSTPP PPPPPPQGPK
130 140 150 160 170 180
SSRLRKLLYL FLTAGLAYAG GVWYSLRSDN FYDFFTEYIP YGEEAVLYLE ERDFRNRFPH
190 200 210 220 230 240
VTKQINRRVT VPKDEGAQVT IPSGSGLSWK VAEEQQEATD MTKKGRRMGT AHANEPTKDI
250 260 270 280 290 300
KVAEKAKEEV KSKSAAKKED VAANIPIQED LEPQPAKAEE RNLDAPRQPA VPAATTIERL
310 320 330 340 350 360
VQDKVDEPVV QDLVKVFNDV ISVISADESA SKFAGPIAKA KEELQRIGDR IVALKKDAQE
370 380 390 400 410 420
SAQEEIRNAH AAFDKSAAEL IRRIDEVRTQ DAAEFREEFE SEREKIARSY QEKVNTELQR
430 440 450 460 470 480
AHEVAEQRLR NELVEQAIEL NRKFLSDVKT LVENEREGRL SKLAELTANV AELERLTAGW
490 500 510 520 530 540
SDVVDINLKT QQLQVAVDAV RTTLENSDVP RPFVRELAAV KELASNDEVV AAAIASISPA
550 560 570 580 590 600
AYQRGIPSAA QLVERFRRVA SEVRKASLLP ENAGITSHAA SLVLSKVMLK KQGLPTGDDV
610 620 630 640 650 660
ESILTRTENF LEEGNFDEAA REMNSLQGWA KLLSKDWLAD VRQVLEVKQA LEIIETEARL
RCLQVE