A6R9K6

PR
Gene name
RPC82 (RPC3, HCAG_06997)
Protein name
DNA-directed RNA polymerase III subunit rpc3
Names
RNA polymerase III subunit C3
Species
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
KEGG Pathway
aje:HCAG_06997
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-325 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6R9K6

Entry ID Method Resolution Chain Position Source
AF-A6R9K6-F1 Predicted AlphaFoldDB

No variants for A6R9K6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6R9K6

No associated diseases with A6R9K6

2 regional properties for A6R9K6

Type Name Position InterPro Accession
domain Ribonuclease H2 subunit B, wHTH domain 94 - 224 IPR019024
domain Rnh202, triple barrel domain 31 - 91 IPR041195

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.

1 GO annotations of molecular function

Name Definition
single-stranded DNA binding Binding to single-stranded DNA.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQYAAELCK LLITDNFGEL YAPLPRIVQN TRLSPRQVRH GLAVLIQQRL IYHYTSLDDG
70 80 90 100 110 120
IAYYEASWMT AYNLVRSGRI LQLVEEKLGK YVAKVLSTIL YHGHVRISYL ETLPELRPQV
130 140 150 160 170 180
SSKAGKLVAA NGLNGIHSDE EEEEEDAHVT DQGEQEEYAS GRPENSVDSD YGKRSASQLH
190 200 210 220 230 240
PALRSLAAYG YIMRVRDAHF QSPADLVEDA ERAVSSRSDV RGLKGKKFQE AIDAGVETYI
250 260 270 280 290 300
KEKTDGTIPQ GPLAGALPRG IKRRAGQLAT NSSSKRVKLE HLPEGDEDID DDDFYGDDYV
310 320 330 340 350 360
DGDNTLMDPN MIISVNYQKF EVALRNRRLA RLAEQCTSRV TSQVYEALLG RIELKTPACR
370 380 390 400 410 420
KQPERVPEGE ENEQYSVAIP LHTILDDIDP DLDLSESMAG VDPANLLSNG HMGLNGDGNG
430 440 450 460 470 480
DDDDDESTGA STGIWNRRRN RVYELEQHLS LLAQEPNIFS TRSMQSGMIT WAVEFRHLAR
490 500 510 520 530 540
RLRHLEIERI IESRFGTIAV RVIRVLAAKG KLDEKRLQEI SLMASKELRQ VLARMEAAGF
550 560 570 580 590 600
VDLQEVPRDA QRQPSRTMYL WFFDLDRVAR MVLEDTYKCM SRCLQRIGVE RNKLKLFLEK
610 620 630 640
TERTDVKGNE EKYLSPAELK TLKEWRDKEA LLLGEVGRLD ELVSVLRDY