A6R8I2

PR
Gene name
CLU1
Protein name
Clustered mitochondria protein homolog
Names
Protein TIF31 homolog
Species
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
KEGG Pathway
aje:HCAG_06623
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

546-640 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6R8I2

Entry ID Method Resolution Chain Position Source
AF-A6R8I2-F1 Predicted AlphaFoldDB

No variants for A6R8I2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6R8I2

No associated diseases with A6R8I2

4 regional properties for A6R8I2

Type Name Position InterPro Accession
repeat Tetratricopeptide repeat 957 - 990 IPR019734
domain CLU domain 291 - 535 IPR025697
domain Clustered mitochondria protein, N-terminal 22 - 94 IPR028275
domain CLU central domain 680 - 842 IPR033646

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
organelle localization Any process in which an organelle is transported to, and/or maintained in, a specific location.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEISVKLPH EPYNIQVTVS SQEQVQDVRQ SIVELPGTFQ YTSFHLEHNG TRINDYIELS
70 80 90 100 110 120
EVKDIQANSE VVLVEDPYTE KEARMHVIRI RELIGAAGDR VDNLHGICAG LSLHDSVAAG
130 140 150 160 170 180
EQLTDTKEGE RGVVRDHALV DYDMTAPPVL QTILPRAQPS LPKTVKAISL SPWNPPPYHL
190 200 210 220 230 240
RQRGHLLYLQ VTTNEGEQHQ ITSHVSGFFV NKSSNAKFDP FPRPAPKNYS AHSLLTLISM
250 260 270 280 290 300
LSPSFDASFK ALQESNNKKD LLTTFPFQNS IPKNPWLVPP TSSAVTAHQS DITRSQENCL
310 320 330 340 350 360
IFGVDNSETL RDWNEEFQST RELPRETVQD KVSRERLTSK LFADYNDAAA RGAVLVAKGE
370 380 390 400 410 420
IAPLNPTEGK DAQIFVYNNI FFSFGADGVG TFASEGGDEA ARVAVGKDVV GAKAVNQLDI
430 440 450 460 470 480
PGLFTPGTVV VDYLGKRLVG QSIVPGIFKQ REPGEHQIDY GGVEGKEVVA EHKDFVPVFE
490 500 510 520 530 540
KLSASLRVKK HPVWDKEGKR HDLEGSVETK GLLGTDGRKY VLDLYRITPL DVAWSEDAEG
550 560 570 580 590 600
HEPYPHRMSV LRLELVELYW RYKMGQYVKA EVQKRKTAKR EAEKTKAVEA QNEDKAELLS
610 620 630 640 650 660
TSDPGEGENK AVASEQERVD ISAFKLALNP DVFSGQVPQT DEEKEEWAQD EKEVRSACDH
670 680 690 700 710 720
LISKVIPELI QDLHDGDVGF PMDGESLTQL LHKRGINVRY LGKLAKLSQA KGQRLLALTA
730 740 750 760 770 780
LLIQEMVSRS FKHIANRYLR YLPSPFTASC VSHLLNCFLG AEVNSNPRPE IDEELREIYP
790 800 810 820 830 840
EGDFSFEKVT PTSLKGDIEK QIKIRFRFNL EPKWTSSLKH LQLLRDISIK LGLQIGAREF
850 860 870 880 890 900
AFERSQIKSQ EHSPEPSSTH SSQDERGKRK KKKGSNSDSP SRVAASPRPV VTFVPEDILN
910 920 930 940 950 960
IVPLVKDASP RSALAEEALE AGRISIMQNQ KEIGQELILE SLSLHEQIYG ILHPEVAKLY
970 980 990 1000 1010 1020
HQLSMLYYQT DEKEAAVELA RKAVIVTERT MGVDSADTIL SYLNLSLFEH ASGNTHTALI
1030 1040 1050 1060 1070 1080
YIRHALELWK IIYGSHHPDS ITTMNNAAVM LQHLKKYPDS RKWFEASLTV CEGLFGRQSI
1090 1100 1110 1120 1130 1140
NTATILFQLA QALALDQDSK AAVNRMRDAY NIFLNELGPN DRNTKEAESW LEQLTQNAVS
1150 1160 1170 1180 1190 1200
IAKHAKDIQA RRLRRTNLSP RMTIGTKPQP QVGQNAPATT NGATSKSIGL DSRSIDELLK
1210 1220 1230
FIEGGGESRS PRSKQKKRAA ASNPKLRGSK QSTVQTA