A6QSQ0

PR
Gene name
FAL1 (HCAG_00406)
Protein name
ATP-dependent RNA helicase FAL1
Names
Species
Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
KEGG Pathway
aje:HCAG_00406
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

368-450 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6QSQ0

Entry ID Method Resolution Chain Position Source
AF-A6QSQ0-F1 Predicted AlphaFoldDB

No variants for A6QSQ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6QSQ0

No associated diseases with A6QSQ0

5 regional properties for A6QSQ0

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 172 - 180 IPR000629
domain Helicase, C-terminal 237 - 398 IPR001650
domain DEAD/DEAH box helicase domain 50 - 212 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 44 - 241 IPR014001
domain RNA helicase, DEAD-box type, Q motif 25 - 53 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADGIDRTAE ERMEFTTSKE VTVAPTFEDM HLKENLLRGI YAYGYESPSA VQSRAIVQIC
70 80 90 100 110 120
KGRDTIAQAQ SGTGKTATFS ISILQVIDTV LRETQALVLS PTRELATQIQ SVVMALGDYM
130 140 150 160 170 180
NVQCHACIGG TNVGEDIRKL DHGQHVVSGT PGRVADMIRR RHLRTRHIKM LVLDEADELL
190 200 210 220 230 240
NRGFREQIYD VYRYLPPATQ VVVVSATLPY DVLDMTTKFM TDPVRILVKR DELTLEGLKQ
250 260 270 280 290 300
YFIAVEKEEW KFDTLCDLYD TLTITQAVIF CNTRRKVDWL TDKMREANFT VSSMHGEMPQ
310 320 330 340 350 360
KERDSIMQDF RQGNSRVLIS TDVWARGIDV QQVSLVINYD LPSNRENYIH RIGRSGRFGR
370 380 390 400 410 420
KGVAINFVTS EDVRILRDIE LYYSTQIDEM PMNGTLFYLR YRPMSRLSLW LTQSNSCRPS
430 440
HVTTLSWSTN VEHTFPLLLM NAFSKIQIGI