A6QFH1
Gene name |
argH |
Protein name |
Argininosuccinate lyase |
Names |
ASAL, Arginosuccinase |
Species |
Staphylococcus aureus (strain Newman) |
KEGG Pathway |
sae:NWMN_0831 |
EC number |
4.3.2.1: Lyases acting on amides, amidines, etc |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6QFH1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6QFH1-F1 | Predicted | AlphaFoldDB |
No variants for A6QFH1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6QFH1 | |||||
No associated diseases with A6QFH1
2 regional properties for A6QFH1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Argininosuccinate synthase, conserved site | 8 - 16 | IPR018223-1 |
| conserved_site | Argininosuccinate synthase, conserved site | 115 - 126 | IPR018223-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.3.2.1 | Lyases acting on amides, amidines, etc |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| argininosuccinate lyase activity | Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine biosynthetic process via ornithine | The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNKAWGGRF | EVQPEEWVDD | FNASITFDQT | LIDQDIEGSI | AHATMLANQG | IISQQDSEQI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IQGLKSIQHD | YHQDQIQFSA | SLEDIHLNIE | HELIKRIGDA | GGKLHTGRSR | NDQVATDMHL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YTKKQVQDII | ALIKSLQSVI | VDIASNNVDT | IMPGYTHLQR | AQPISFAHHI | MTYFWMLQRD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QQRFEDSLKR | IDINPLGAAA | LSGTTYPIDR | HETTALLNFG | SLYENSLDAV | SDRDYIIETL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HNISLTMVHL | SRFAEEIIFW | STDEAKFITL | SDAFSTGSSI | MPQKKNPDMA | ELIRGKVGRT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TGHLMSMLMT | LKGLPLAYNK | DMQEDKEGLF | DAVHTIKGSL | RIFEGMIQTM | TINKERLNQT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VKEDFSNATE | LADYLVTKNI | PFRTAHEIVG | KIVLECIQQG | HYLLDVPLAT | YQQHHSSIDA |
| 430 | 440 | 450 | |||
| DIYDYLQPEN | CLKRRQSYGS | TGQSSVKQQL | DVAKQLLSQ |