A6QAM9

PR
Gene name
dapD
Protein name
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Names
Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase
Species
Sulfurovum sp (strain NBC37-1)
KEGG Pathway
sun:SUN_1588
EC number
2.3.1.117: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

310-397 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6QAM9

Entry ID Method Resolution Chain Position Source
AF-A6QAM9-F1 Predicted AlphaFoldDB

No variants for A6QAM9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6QAM9

No associated diseases with A6QAM9

2 regional properties for A6QAM9

Type Name Position InterPro Accession
repeat Hexapeptide repeat 297 - 330 IPR001451
domain 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain 174 - 214 IPR032784

Functions

Description
EC Number 2.3.1.117 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAIETVASTD AFKVLVAEVT AQEGYREPMA FGIARVDRGQ KNAEKVLQAN FPLINWKENF
70 80 90 100 110 120
GSAAVFIKAL QEAKCDVDFS GSEFVATIND NFVANAMAAF APYLAEATGD SHKNVQVIKT
130 140 150 160 170 180
LAKMEDIGKN FRIVFLFEDA NPESVEAVYL KLYALSLRKA ELRKVNLNGA FGILSNVAWV
190 200 210 220 230 240
GNTPYELDYL RENEIEMKLN GTYPTVDSVD KFPRFLQHVI PDDNTRILEA SKVRMGAQLA
250 260 270 280 290 300
AGTTVMPGAS YINFNAGTLG PVMVEGRISS SAIVGAGSDV GGGASILGVL SGTDGNPISI
310 320 330 340 350 360
GENTLLGANS VTGLPLGDGC IVDAGITILA GTKIKIAPEE LEKIKAANPD AKLDNKTTFK
370 380 390
GEELQGLNGI HYRQNSLTGE IIARRSTREV KLNEDLH