A6Q5J0

PR
Gene name
dapD
Protein name
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Names
Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase
Species
Nitratiruptor sp (strain SB155-2)
KEGG Pathway
nis:NIS_1643
EC number
2.3.1.117: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

338-393 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6Q5J0

Entry ID Method Resolution Chain Position Source
AF-A6Q5J0-F1 Predicted AlphaFoldDB

No variants for A6Q5J0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6Q5J0

No associated diseases with A6Q5J0

2 regional properties for A6Q5J0

Type Name Position InterPro Accession
repeat Hexapeptide repeat 293 - 324 IPR001451
domain 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain 170 - 210 IPR032784

Functions

Description
EC Number 2.3.1.117 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIQTKDDFFA LVNEIQSSAY YKEPLAFGIA RVDRGQKNPE KILQATFPFI NWKENYGSAA
70 80 90 100 110 120
IFQKALHETG KLLNDESEAV YDVTKNFVAE ALSYCNPWIE EAIGDAHKNV QVIKYLSTLD
130 140 150 160 170 180
EEELANFKIV FLFEDAAPKS VEAVYLKLYA LSTGKAALRS VNLNGAFGIL HNVAWSGTTP
190 200 210 220 230 240
IELDWLRENE LELKMSGQYP VIDSVDKFPR FLQHIIPADN TRILDAAKVR MGAQLAAGTT
250 260 270 280 290 300
VMPGASYINF NAGTLGPVMV EGRISSSAVV GKGSDVGGGA SILGVLSGTS GNPISIGENC
310 320 330 340 350 360
LLGANSVTGI PLGNGCIVDA GIAVLEGTKF FMSEADYEKI KEANPEWNAE YKEFFKGREL
370 380 390
AGLSGLHFRQ DSTSGQMKVF RSNKEVKLNE ELH