A6Q4D7

PR
Gene name
dapE
Protein name
Succinyl-diaminopimelate desuccinylase
Names
SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Species
Nitratiruptor sp (strain SB155-2)
KEGG Pathway
nis:NIS_1237
EC number
3.5.1.18: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

40-110 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6Q4D7

Entry ID Method Resolution Chain Position Source
AF-A6Q4D7-F1 Predicted AlphaFoldDB

No variants for A6Q4D7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6Q4D7

No associated diseases with A6Q4D7

3 regional properties for A6Q4D7

Type Name Position InterPro Accession
domain Dihydrodipicolinate reductase, N-terminal 3 - 106 IPR000846
domain Dihydrodipicolinate reductase, C-terminal 110 - 244 IPR022663
conserved_site Dihydrodipicolinate reductase, conserved site 128 - 145 IPR022664

Functions

Description
EC Number 3.5.1.18 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
cobalt ion binding Binding to a cobalt ion (Co).
succinyl-diaminopimelate desuccinylase activity Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVIDLFKKL LSFPSITPDD AGSLEFIREY LSDFHALWFN KHGVKNLFLY KKFGEGEHLC
70 80 90 100 110 120
FAGHVDVVPP GDGWESDPFE PLEKDGFIYA RGAQDMKSGV AAFVQAVKEA KVFHGTLSLL
130 140 150 160 170 180
LTSDEEGEAK WGTKYALEEL ERMHMTPQYA IVAEPTCEER FGDAIKIGRR GSINGVIEKI
190 200 210 220 230 240
GKQGHAAYPE KAVNPIHKVA QVLPKMAGVD LDSGDEYFAP SKFVITDIRA GMEVTNVTPG
250 260 270 280 290 300
RLKMMFNVRN NTKTTMQDVE RFVHRYFDGM NYTLKLSQSA KPFLTDPNSK VVQVIDQAIK
310 320 330 340 350 360
KMTGITPKHS TAGGTSDARF FAEYGVKTIE FGVKNDTIHA PNERTSKEEV EKLYLVFKEV
IRSF