A6LP38
Gene name |
tmcAL |
Protein name |
tRNA(Met) cytidine acetate ligase |
Names |
|
Species |
Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429) |
KEGG Pathway |
tme:Tmel_1854 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6LP38
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6LP38-F1 | Predicted | AlphaFoldDB |
No variants for A6LP38
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6LP38 | |||||
No associated diseases with A6LP38
5 regional properties for A6LP38
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Helix-hairpin-helix DNA-binding motif, class 1 | 81 - 100 | IPR003583 |
| conserved_site | Uncharacterised protein family UPF0758, conserved site | 188 - 193 | IPR020891 |
| domain | RadC-like JAB domain | 118 - 235 | IPR025657 |
| domain | MPN domain | 116 - 239 | IPR037518 |
| domain | UPF0758, N-terminal | 9 - 95 | IPR046778 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ligase activity, forming carbon-nitrogen bonds | Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. |
| tRNA binding | Binding to a transfer RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKVLGVIVEY | NPFHNGHLYH | LQQAKKIVSP | DYVIAIMSGN | FCQRGEPAII | NKFARAEIAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KNGIDVVFEL | PTVYALQDAG | GFAFGAITLL | DKLTVVTDVV | FGSESADKNF | ITTVAKTLLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NPDKFDNLLK | IELKKGLSFP | NARKFALKKF | LNENEDFLKM | IENSNDILGI | EYVKSILKLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKINYHLIKR | IGAKYNDTEL | ESKYSSATAI | RNAIVRNNPF | ETYVPQTSYK | VLKREFSYGR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GPVSLENMEQ | FILTFLRLKH | RKDFESIYSF | TEGLDQRFIK | AIKTSKKLSD | FLEKVKTKRF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TYSRIRRAIF | HALFDFKKEY | IEFSNKLGTQ | YARILGFTKK | GQKLLSKIKK | ASKIPIISNP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SLHEKVLKKV | LTDKDRKWEV | NKKLFIWQFE | KDIVASNIYT | MFYPQKNERK | YGLDFRKPII |
| EGENE |