A6L997

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
KEGG Pathway
pdi:BDI_0484
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

734-819 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6L997

Entry ID Method Resolution Chain Position Source
AF-A6L997-F1 Predicted AlphaFoldDB

No variants for A6L997

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6L997

No associated diseases with A6L997

9 regional properties for A6L997

Type Name Position InterPro Accession
domain Helicase, C-terminal 604 - 788 IPR001650
conserved_site SEC-C motif 1106 - 1123 IPR004027
domain SecA DEAD-like, N-terminal 7 - 584 IPR011115
domain SecA Wing/Scaffold 771 - 1017 IPR011116
domain SecA, preprotein cross-linking domain 399 - 540 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 177 - 336 IPR014001
domain SecA motor DEAD 4 - 772 IPR014018
conserved_site SecA conserved site 682 - 697 IPR020937
domain SecA, C-terminal helicase domain 602 - 742 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFNEFMTKL FGNKSQRDLK EITPYVDKVK AVYPSIKALS NDELRAKTDE IKQRIQDYVA
70 80 90 100 110 120
EEKAQVEELR KGIEDKELEE REAIWAEVDK IEKAITDKME VVLEQSLPEV FAIMKDTARR
130 140 150 160 170 180
FAENEEVVVT ANQFDRDLAA RFDFVRIEDD KAIYANHWKA GGNEITWDMI HYDVQLFGGV
190 200 210 220 230 240
VLHKGKIAEM ATGEGKTLVA TLPVFLNALT RNGVHVVTVN DYLSKRDSEW MGPLYMFHGL
250 260 270 280 290 300
SVDCIDKHQP NSEARRKAYE ADITFGTNNE FGFDYLRDNM AISPKDLVQR KHNYSIVDEV
310 320 330 340 350 360
DSVLIDDART PLIISGPIPR GEEQLFEQFR PNVEVVVNAQ KDLCSKLLIE AKKKMASDDQ
370 380 390 400 410 420
KVVEEGSILL YRSFKGYPRN KALIKFLSEQ GVKAQMLKTE EYFMSENMRH MHEATDELYF
430 440 450 460 470 480
VIDEKNNSIE LTDKGIDLLT GKTDDPTFFV LPDITSQLSQ LENMTGTEEE KQAQKDEILA
490 500 510 520 530 540
NYSVKSERVH TINQLLKAYT LFEKDDEYVV MDNKVMIVDE QTGRIMDGRR YSDGLHQAIE
550 560 570 580 590 600
AKERVKVEAA TQTFATITLQ NYFRMYHKLS GMTGTAETEA GEFWDIYKLD VVVIPTNRPI
610 620 630 640 650 660
ARNDMNDRIY KTKREKYNAV IEEIVQLTEA GRPVLVGTTS VEISELLSRM LTMRKIQHNV
670 680 690 700 710 720
LNAKLHQKEA EIVALAGQKS TVTIATNMAG RGTDIKLSKD VKDAGGLAII GTERHESRRV
730 740 750 760 770 780
DRQLRGRAGR QGDPGSSVFF VSLEDDLMRL FASEKIAGLM DKLGFKEGEV LEHNMLSKSV
790 800 810 820 830 840
ERAQKKVEEN NFGIRKRLLE YDDVMNSQRN VIYTRRRHAL MGERIGLDVL NTIYDTSTAI
850 860 870 880 890 900
ADQHAEDFEG FKLELFKTFA MESPFTEDEF KSMKPEQLVE KLFEEALKTY KRRMERMTQV
910 920 930 940 950 960
AHPVIKQVYE NQGAMYENIM IPITDGKRMY NVSCNLKEAY DTECKAIVKS FQKSIVLHMI
970 980 990 1000 1010 1020
DEGWKEHLRE MDELRHSVQN ASYENKDPLL IYKLESYNLF KTMVDNMNRK TAAILMRGQI
1030 1040 1050 1060 1070 1080
PVREEPTEEQ RQAMQARQAA VAQQAAQAIA EERARQRIAV QEAAPEKHED MSRYRTEKTD
1090 1100 1110 1120
LSGNNTQAEA PQPKQAPVRA EKRVGRNDPC PCGSGKKYKN CHGQGL