A6L030

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) (Bacteroides vulgatus)
KEGG Pathway
bvu:BVU_1355
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

118-438 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6L030

Entry ID Method Resolution Chain Position Source
AF-A6L030-F1 Predicted AlphaFoldDB

No variants for A6L030

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6L030

No associated diseases with A6L030

5 regional properties for A6L030

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 502 - 672 IPR000795
domain Small GTP-binding protein domain 507 - 656 IPR005225
domain Translation initiation factor IF-2, N-terminal 427 - 478 IPR006847
domain Translation initiation factor IF- 2, domain 3 781 - 893 IPR023115
domain Translation initiation factor IF-2, domain II 678 - 773 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTIRLNKVTR DLNVGITTVV EFLQKKGYTI EASPNAKITE EQYAVLVKEF STDKNLKIES
70 80 90 100 110 120
EKFSQERQNK DRNKASISIE GFESKKEKEE VVKTVIPEEA RPKLKQVGKI DLDNLNKKTA
130 140 150 160 170 180
PKVVEPAAKV IEQTPKAEPV VEKVVERKET PQPEKETPKP VVVEEKKPEP APQPAPAPVL
190 200 210 220 230 240
EEKKEPKIEK TEEKTPQVKE MEKETPEAAP VQEKEEDDVF KIRPTEFKSK INVVGQIDLA
250 260 270 280 290 300
ALNQSTRPKK KSKEEKRKER EEKDKQRQEQ RKLMKDAIIK EIRKGDDKIS KNSVNDDAAK
310 320 330 340 350 360
KKKRNRINKE RVDINAAGTT NAGGASNNNQ RNDNANRPNR NNNSKPNGNN NQGGGKFNKD
370 380 390 400 410 420
RFKKPVVKAE VSDEDVAKQV KETLARLTNK TKNKAAKYRK EKRENVQNRL MEQEEMEQED
430 440 450 460 470 480
SKILKLTEFV TANELASMMD IPVTQVIATC MSIGIMVSIN QRLDAETINL VAEEFGYKTE
490 500 510 520 530 540
YVSAEVAQAI TEEEDNEEDL QPRAPIVTVM GHVDHGKTSL LDYIRKANVI AGEAGGITQH
550 560 570 580 590 600
IGAYNVKLED GRHITFLDTP GHEAFTAMRA RGAKVTDIAI IIVAADDNVM PQTKEAINHA
610 620 630 640 650 660
MAAGVPIVFA INKVDKPHAN PDKIKEELAA MNFLVEEWGG KYQSQDISAK KGTGVHDLLE
670 680 690 700 710 720
KVLLEAEMLD LKANPDRKAT GSIIESSLDK GRGYVATMLV ANGTLKMGDI VLAGTSYGKV
730 740 750 760 770 780
KAMFNERNQR IKEAGPSEPV LILGLNGAPA AGDTFHVIDT EQEARDIANK REQLQREQGL
790 800 810 820 830 840
RTQKLLTLDE VGRRLALGDF HELNVIVKGD VDGSVEALSD SLIKLSTEQV QVNVIHKGVG
850 860 870 880 890 900
QISESDVTLA AASDAIIVGF QVRPSSSAGK LAEQEGVDIR KYSVIYDAIE EVKAAMEGML
910 920 930 940 950 960
APTLKEQITA TIEVREVFNI TKVGLVAGAM VKTGKVKRSD KARLIRDGIV VFTGAINALK
970 980 990 1000
RFKDDVKEVG TNFECGISLT NCNDIKVGDI IEAYEEVEVK QTL