Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6H8T2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6H8T2-F1 | Predicted | AlphaFoldDB |
No variants for A6H8T2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A6H8T2 | |||||
No associated diseases with A6H8T2
1 regional properties for A6H8T2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Vinculin, conserved site | 178 - 198 | IPR000633 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| axoneme | The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-tubulin binding | Binding to the microtubule constituent protein beta-tubulin. |
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPPKDGKSAK | KKGGISKAEK | ERLQREEEEK | RQREAEEARL | IAEREENERL | ERERIEQEKQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HILELKDRER | REDELNELRH | ILDENHFAVT | VWEAECREKS | KWERYMLCDG | SPDPSVQPEI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NTYISLWRDD | SENQIQKVLE | ECALTLELEK | ELEFLLGDGP | EPSIAEQYQE | TLLSLQNLIH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YKLNQATEEL | LKFANYNSDI | DTGNMQTVVK | DSNITLCLWA | NLNKNPRFKG | YKFEEVGLGF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELPKPLAVIE | VAVRILHTRY | DHLSHHSERE | QLQKRRSMME | AILTQNTESS | AAVHNGKMEG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERDESESSKQ | VDECHSVRSE | SRKRSAVSVI | SAKEGRKSSS | IKLLEEGESQ | MEEITTTLEA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DQHDPYPSPA | EPVTDTDVHI | VDLQQFTPLG | GVFYFDLFHM | PPQSRTVKGW | EMRELLDTGL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QVFPYPTEQS | RIQSSTSVKL | DEHSNTTVAS | LPVGVTVALP | HSVLFLEDPQ | VARWDPIGQH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| WRTDCISETS | YDAELRTISF | QMTAFYAFTL | LQETYANMPF | QSWELRPLGQ | DSALFTITGA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LIEVSITVKG | KQCMLHTEET | KDLDRLLGKW | MSPSELQKAM | RKAGINIFVN | EYSDKYVSIN |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LKDPLIEHAV | YEQMALMSSA | VAFSWSRWNA | QCRQEHLVLQ | ACEQLEVGPV | AEKAWSLYLL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GAQRNQHLKM | KEQEDSFSPE | LAEGSEFHST | FLHMLRQDLS | TEGQARVRQS | HHLYIDTVQR |
| 730 | |||||
| LLCATRVLTY | S |