Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A6H5X4

Entry ID Method Resolution Chain Position Source
AF-A6H5X4-F1 Predicted AlphaFoldDB

28 variants for A6H5X4

Variant ID(s) Position Change Description Diseaes Association Provenance
rs253801866 7 P>S No EVA
rs3389307726 9 C>R No EVA
rs3389330637 10 G>A No EVA
rs3389337635 11 P>L No EVA
rs36239564 17 S>C No EVA
rs3389350445 31 C>S No EVA
rs3389335644 38 S>N No EVA
rs3389345947 59 S>P No EVA
rs3389345983 79 K>* No EVA
rs3389332533 86 W>* No EVA
rs3389307723 89 R>S No EVA
rs230818677 109 F>S No EVA
rs262245385 113 S>N No EVA
rs6398785 125 I>V No EVA
rs259679587 145 E>K No EVA
rs259679587 145 E>Q No EVA
rs255461244 157 S>N No EVA
rs3389335683 174 A>T No EVA
rs3389335158 183 N>K No EVA
rs38420856 183 N>S No EVA
rs36380480 202 S>A No EVA
rs3389298561 203 P>S No EVA
rs586688027 259 L>V No EVA
rs578865709 282 Q>K No EVA
rs3389337688 298 Q>* No EVA
rs1133146636 323 S>C No EVA
rs3389289249 332 G>D No EVA
rs3389350535 335 D>E No EVA

No associated diseases with A6H5X4

2 regional properties for A6H5X4

Type Name Position InterPro Accession
domain Zinc finger, PHD-type 92 - 143 IPR001965
domain Extended PHD (ePHD) domain 25 - 143 IPR034732

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5I0E2 Phf11 PHD finger protein 11 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MAQETAPPCG PVSRGDSPII EKMEKRTCAL CPEGHEWSQI YFSPSGNIVA HENCLLYSSG
70 80 90 100 110 120
LVECETLDLR NTIRNFDVKS VKKEIWRGRR LKCSFCNKGG ATVGCDLWFC KKSYHYVCAK
130 140 150 160 170 180
KDQAILQVDG NHGTYKLFCP EHSPEQEEAT ESADDPSMKK KRGKNKRLSS GPPAQPKTMK
190 200 210 220 230 240
CSNAKRHMTE EPHGHTDAAV KSPFLKKCQE AGLLTELFEH ILENMDSVHG RLVDETASES
250 260 270 280 290 300
DYEGIETLLF DCGLFKDTLR KFQEVIKSKA CEWEERQRQM KQQLEALADL QQSLCSFQEN
310 320 330
GDLDCSSSTS GSLLPPEDHQ VRSQESPEVQ AGSGDSL