A6GX63

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
KEGG Pathway
fps:FP0581
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

998-1097 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6GX63

Entry ID Method Resolution Chain Position Source
AF-A6GX63-F1 Predicted AlphaFoldDB

No variants for A6GX63

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6GX63

No associated diseases with A6GX63

8 regional properties for A6GX63

Type Name Position InterPro Accession
domain Helicase, C-terminal 610 - 786 IPR001650
domain SecA DEAD-like, N-terminal 8 - 582 IPR011115
domain SecA Wing/Scaffold 769 - 1017 IPR011116
domain SecA, preprotein cross-linking domain 398 - 538 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 179 - 338 IPR014001
domain SecA motor DEAD 5 - 770 IPR014018
conserved_site SecA conserved site 680 - 695 IPR020937
domain SecA, C-terminal helicase domain 600 - 740 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFINNILKV FVGDKSQKDV KAIQPIIAKI RTLENSLSNL SHDELRAKTV YFKDIIKQAR
70 80 90 100 110 120
AEKDTKIENL KLEVEAIQDI DAREDVYAQI DILEKEAYEI SEKTLNEILP EAFAVIKETA
130 140 150 160 170 180
KRFKENKQIT VTATAKDREL SATKSYINLV GDTAVWANSW SAAGKEITWD MIHYDVQLIG
190 200 210 220 230 240
GVVLHQGKIS EMQTGEGKTL VATLPLYLNA LTGNGVHLVT VNDYLAKRDS AWKAPLFEFH
250 260 270 280 290 300
GLMVDCIDLH QPNSDARRKA YDADITYGTN NEFGFDYLRD NMAHSPEDLV QRKHNFAIVD
310 320 330 340 350 360
EVDSVLIDDA RTPLIISGQV VDGDRHEFTE LKPKIENLVN IQRQLANGFL TEAKRLIKEG
370 380 390 400 410 420
NTKDGGFQLL RAHRALPKNK ALIKFLSEEG IKALLQKTEN QYMSDNNREM PKVDEALYFV
430 440 450 460 470 480
IEEKNNQVEL TDSGIEIMSK DTEDTFFVLP DIGTEIARIE KLNLSTEEQG EQKEKLFQDF
490 500 510 520 530 540
SVKSERIHTL TQLLKAYTLF EKDTEYVLMD NKVMIVDEQT GRIMDGRRYS DGLHQAIEAK
550 560 570 580 590 600
ENVKIEDATQ TYATVTLQNY FRMYSKLAGM TGTAVTEAGE LWEIYKLDVV EIPTNRGMSR
610 620 630 640 650 660
IDKEDLIYRS VREKFNAVIE DVVGLSQSGR PVLIGTTSVE ISELLSRMLK MRNIPHNVLN
670 680 690 700 710 720
AKMHKQEAQI VEEAGKPGVV TIATNMAGRG TDIKLTAEVK AAGGLAIIGT ERHDSRRVDR
730 740 750 760 770 780
QLRGRAGRQG DPGSSQFYVS LEDNLMRLFG SDRVAKIMDR MGLQEGEVIQ HSMMTKSIER
790 800 810 820 830 840
AQKKVEENNF GTRKRLLEYD DVMNSQREVV YKRRRHALHG ERLKLDIANM MYDTCEVIVE
850 860 870 880 890 900
KNKLTGDFKN FEFELIKNLS ITSPVTQADF AKLSDIELTG KTYKAASEYY TEKNIRDAHE
910 920 930 940 950 960
AFPIIRNVYE NPGNSFERII VPFTDGIKSL NVVTDLKKAY ESQGKQLVAD FEKNITLAIV
970 980 990 1000 1010 1020
DDAWKKHLRK MDEMKQSVQL AVHEQKDPLL IYKFEAFKLF KNMLDGINKE VISFLFKGDL
1030 1040 1050 1060 1070 1080
PQQQNNIQEA TQIRQKENYI ESKDEILNIE EQAERNHEAG QTQQHQVTET IVRDMPKINR
1090 1100 1110
NDTVKIQNVA NGQIEELKFK KAEILLNAGT WVLVSE