A6GWV8

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)
KEGG Pathway
fps:FP0470
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

102-401 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6GWV8

Entry ID Method Resolution Chain Position Source
AF-A6GWV8-F1 Predicted AlphaFoldDB

No variants for A6GWV8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6GWV8

No associated diseases with A6GWV8

5 regional properties for A6GWV8

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 465 - 635 IPR000795
domain Small GTP-binding protein domain 470 - 607 IPR005225
domain Translation initiation factor IF-2, N-terminal 390 - 441 IPR006847
domain Translation initiation factor IF- 2, domain 3 743 - 855 IPR023115
domain Translation initiation factor IF-2, domain II 641 - 734 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEGTIRINK VLREFNISLE RAVDYLKDKG HVIESNPNTK ISDEVYNVLS NQFAGDKGNK
70 80 90 100 110 120
DASKEVGEEK RKEKEALRVE RENEIEEKRK VDEERQRQEV IRAKAVVTGL KQVGTIDLSA
130 140 150 160 170 180
KSVIKPTIIP GVKAEAKAEV KTEAKVEAKT EVKVEVKVEP KAEMPVAKTP EKSEQPKQHV
190 200 210 220 230 240
AKETLVKEKI FAKEPAKNVA KPIVGKTPEA TSKPSVEDAP VDETHETKYT KLTGPTFSGQ
250 260 270 280 290 300
TIDLSQFNKP KKIIEPNKGG AKPAGAGNNN NNKNKRKRIP TKSGEANATP RVPGTNLIRP
310 320 330 340 350 360
NTGGNATGGG FNRANKPGFV KGARPAIVPK VEPTEEDVKN QIKETLERLQ GKGNKSKAAK
370 380 390 400 410 420
YRRDKRDTHR QKSDDEQREL EAGSKTIKVT EFVTVGEVAT MMDVPITKVI GTCMSLGIMV
430 440 450 460 470 480
TMNQRLDAET LTIVCDEFGF EVEFITTDLE ENIEVVEDSA EDLVHRAPIV TVMGHVDHGK
490 500 510 520 530 540
TSLLDYIRKT NVIAGESGGI TQHIGAYGVE LENGQKIAFL DTPGHEAFTA MRARGAQVTD
550 560 570 580 590 600
IAIIVVAADD DIMPQTKEAI SHAQAANVPI IFAINKVDKQ NANPEKIKEK LAAMNFLVED
610 620 630 640 650 660
WGGKYQSQDI SAKTGIGMKE LLEKVLLEAE VLDLKANPNK PATGTVVEAF LDKGRGYVST
670 680 690 700 710 720
VLVQAGTMRV GDYILAGKNH GKIKAMQDER GNNVTEAGPS TPISILGLAG APTAGDKFNI
730 740 750 760 770 780
FADEREAKAI AAKRTQLMRE QSVRVQRHIT LDEIGRRIAL GQFKELNIIL KGDVDGSVEA
790 800 810 820 830 840
LSDSFSKLST PEIQINIIHK GVGAITETDV MLASASDAII IGFNVRPAGN AKQLAEKEEI
850 860 870 880 890 900
DIRHYSIIYA AIDDLRDAME GMLSPEMKEE ITGLAGVREL FKISKVGTIA GCMITDGKIL
910 920 930 940 950 960
RANKVRVIRD NVVIHTGDII ALKRFKDDVK EVAKGYDCGI QIKGFNEIEI DDIIEGFTEV
AVKRKLK