A5YVF1

PR
Gene name
SGS3
Protein name
Protein SUPPRESSOR OF GENE SILENCING 3
Names
SlSGS3
Species
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
KEGG Pathway
sly:100134882
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

51-138 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5YVF1

Entry ID Method Resolution Chain Position Source
AF-A5YVF1-F1 Predicted AlphaFoldDB

No variants for A5YVF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5YVF1

No associated diseases with A5YVF1

2 regional properties for A5YVF1

Type Name Position InterPro Accession
domain XS domain 301 - 415 IPR005380
domain Zinc finger-XS domain 233 - 270 IPR005381

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, perinuclear region
  • Accumulates in inclusion bodies in the cell periphery
  • May interact with the ER network from the perinuclear region out to the cell periphery (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
perinuclear region of cytoplasm Cytoplasm situated near, or occurring around, the nucleus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
gene silencing by RNA A process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
regulation of defense response to virus Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFSKWGGKP SNSSEKQKAS STPTVEEINR GVGDIGLNSE QNEGWEVYAR KPKNKGGSSA
70 80 90 100 110 120
GKQWAPQNPS PKAWGNQNTK AWGHPDVGKK SGTRNNAGSG RGSGNNWSTP SDPQKLARPH
130 140 150 160 170 180
LYDGGFPSSA PVPPALKNGW DWSSRVASAH PKDNSQVAAA ADDDKASEHD AEDNELDFLD
190 200 210 220 230 240
ESDDDLHSDD FDSDVGEMSY ETRKKNPWFN QLFHSLDSLT VTEINEPERQ WHCPACKGGP
250 260 270 280 290 300
GAIEWFTGLQ SLMTHAKTKG LRVKIHRELA ELLEEDLRQR GTSVVPPGEV YGRWGGMEFK
310 320 330 340 350 360
DKEIVWPPMV IIMNTRLDKD ENDKWIGMGN QELLEYFSSY AAVKARHSYG PQGHRGMSLL
370 380 390 400 410 420
IFEASAVGYI EADRLSEHFS ENGRNRDAWE RRSARFYPGG KRLLYGYMAD KKDIDNFNQH
430 440 450 460 470 480
SAGKSKLKFE MRSYKEAVWN PAKQMREDNQ QLIWFKNKAA KHQMQAKALE ESLSLVSEKH
490 500 510 520 530 540
RQTLEENKIV RLKTKMHHEQ IKEEMEFQEQ FFKDQIKIIH DARTAREDNF EKTQQEQREM
550 560 570 580 590 600
VKQSNANTAS VEDHRVRAEK VAKFIKLQDK EMEEFVEERE NLMRTHDDRI AALRRKYWEE
610 620 630
EVELERKFDL ELSKLMEKYS PKQSDEVNSS GTM