A5WUY6

PR
Gene name
stpg1 (si:dkey-218f9.1)
Protein name
O(6)-methylguanine-induced apoptosis 2
Names
MAPO2, Sperm-tail PG-rich repeat-containing protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

8-264 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5WUY6

Entry ID Method Resolution Chain Position Source
AF-A5WUY6-F1 Predicted AlphaFoldDB

No variants for A5WUY6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5WUY6

No associated diseases with A5WUY6

2 regional properties for A5WUY6

Type Name Position InterPro Accession
repeat Sperm-tail PG-rich repeat 213 - 223 IPR010736-1
repeat Sperm-tail PG-rich repeat 254 - 266 IPR010736-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
female pronucleus The pronucleus originating from the ovum that is being fertilized.
germinal vesicle The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
male pronucleus The pronucleus originating from the spermatozoa that was involved in fertilization.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
chromatin binding Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
histone binding Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.

3 GO annotations of biological process

Name Definition
DNA demethylation of male pronucleus The active DNA demethylation of the paternal genome that takes place before the first cell division.
positive regulation of DNA demethylation Any process that activates or increases the frequency, rate or extent of DNA demethylation.
positive regulation of mitochondrial membrane permeability involved in apoptotic process Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGKLHRGLAE FNGCASSIPP KYQTVIISNE EKKGFSSQSR RFEEYLNESP GPGSYLSHSP
70 80 90 100 110 120
AEGCSPSFSK RGTGSFASKG GRVPRSFQRL SPGPDAYNLQ MSLLHKHDFN RGESRIFRLP
130 140 150 160 170 180
YALKKEKPNN ENPAPNQYDV SYRAVDKNST ISGESAFRSK TRRSAVVSDK FKGPSPCHYK
190 200 210 220 230 240
VSDVLVQKSP QALVSCFKSK TARIQSPVRN NIPGPGTYNP HQPPEPVKRT VLPRRYYLGL
250 260 270 280 290 300
SAPPLIPEKV PPFPGPGHYD IVNYNRPVKH MVSSAAFLSG TNRHMQEVKG QDIPGPGFYE
310
PTVLSKTSFL YNPAKLWIPA