A5VN81

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
KEGG Pathway
bov:BOV_0139
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

786-857 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5VN81

Entry ID Method Resolution Chain Position Source
AF-A5VN81-F1 Predicted AlphaFoldDB

No variants for A5VN81

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5VN81

No associated diseases with A5VN81

6 regional properties for A5VN81

Type Name Position InterPro Accession
domain ACT domain 696 - 779 IPR002912-1
domain ACT domain 802 - 874 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 71 - 107 IPR002934
domain HD/PDEase domain 451 - 605 IPR003607
domain HD domain 455 - 588 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 180 - 318 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAHDLKLEE IVNAETLRRK LNELADTADE SYTSLPMRKV VLQTLKDALA SGRANAEDML
70 80 90 100 110 120
MKDGGGTLCA KRLCYLMDTL IDILFEFATT RAYPTRNPSK AENMALVAVG GYGRGGLAQG
130 140 150 160 170 180
SDIDLLFLLP YKQTPWGEQV VEYTLYMLWD MGLKVGHSTR NIDECIRLAR EDMTIRTALL
190 200 210 220 230 240
DARFLTGDKD LFRTLEIRFE EEIVKGTEPE FIQAKLAERD ARHRKAGETR YLVEPNVKEG
250 260 270 280 290 300
KGGQRDLHTL FWITKYFYRV KTKEELVKLG VLSRAELKLF NKAEDFLWAV RCHMHFATLK
310 320 330 340 350 360
AEERLSFDIQ PEIAQRLGYT AHPGQNYVER FIKHYFLVAK DVGDLTRIIC AALEEQQAKH
370 380 390 400 410 420
VPGFNRIFLT FSRRKRKLSD DGAFISENHR INIARPDIFR QDPVNMIRLF HLADRHGLEF
430 440 450 460 470 480
HPEAMQSLTR SLKLINADLR ENPEANRLFL EILTSPRNPE LILRRMNESG VLGKFIPDFG
490 500 510 520 530 540
KIVAMMQFNM YHHYTVDEHL LRCIAVLSEI EHGELKTEHP LSNHLITTIK RDRNLLYVTL
550 560 570 580 590 600
LLHDIAKGRP EDHSIAGARI ARRLCPRFGL TPSETETVEW LVREHLTMSM VAQSRDLNDR
610 620 630 640 650 660
KTIIDFADTV QTMERLKLLL ILTVCDIKAV GPGIWNGWKG QLLRTLFYET ELVLTGGFSE
670 680 690 700 710 720
LSRAARDKQA REALAERLSD WPKEERDAYL ALPYTNYFLT VSLDDQVRHA HFIRDADQQG
730 740 750 760 770 780
RALVTMAKPH AFEAVTEITV LAPDHPRLLS VITGACAAAG GNIVDAQIFT TSDGRALDTI
790 800 810 820 830 840
LISREFDTDD DERRQAERVG KVIEDVLSGK AHLPDMLAKR TKPKKAARAF KVEPRVEINN
850 860 870 880 890 900
TLSNKFTVIE VEGLDRPGLL SELTGLISDL SLDIASAHIT TFGEKVIDSF YVTDLVGHKI
910 920 930
SNATRQGNIK RKLLALLGAE NGARTNGRSP QAAA